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Florquinitau (18F)
go.drugbank.com/drugs/DB19215ApprovedFlorquinitau F 18 is a radioactive diagnostic drug used as a fluorine-18–labeled positron emission tomography (PET) tracer. … [L64052] It is used to identify tau NFT pathology in adults with cognitive impairment being evaluated for Alzheimer's disease and has not been established for evaluating non-Alzheimer's tauopathies.
Synonyms: 5-isoquinolinamine, 6-(fluoro-18f)-3-(1h-pyrrolo(2,3-c)pyridin-1-yl)-, 6-fluoro-3-(1h-pyrrolo(2,3-c)pyridin-1-yl)isoquinolin-5-amineCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesOzanimod
go.drugbank.com/drugs/DB12612ApprovedInvestigational[A189336] In clinical trials, Ozanimod has been shown to be well-tolerated and has resulted in a higher decrease in the rate of MS relapses than with intramuscular [interferon beta-1a], a current standard … Ozanimod is a once-daily sphingosine 1-phosphate receptor modulator for the treatment of relapsing Multiple Sclerosis (MS) and inflammatory bowel disease.
Mixtures: ZEPOSIA 7-Day Starter Pack, ZEPOSIA 7-Day Starter PackCategories: Sphingosine 1-phosphate Receptor Modulator, Sphingosine 1 Phosphate Receptor ModulatorsInsulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigational[L50763] It has also been approved in Japan and Australia. … [A264093] These modifications - which cause increased serum albumin binding and attenuated insulin receptor affinity - result in a mean half-life of approximately 196 hours, allowing for once-weekly administration
Brinzolamide
go.drugbank.com/drugs/DB01194Approved[A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse … [A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate.
Mixtures: BRİTİL-T 10 MG/ML + 5 MG/ML GÖZ DAMLASI, SÜSPANSİYON, 1 ADET, BRIDINE®Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesMycophenolate mofetil
go.drugbank.com/drugs/DB00688ApprovedInvestigational[A180826] In addition to the above uses, mycophenolate mofetil has also been studied for the treatment of nephritis and other complications of autoimmune diseases. … Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid, and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH).
Synonyms: 2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoateCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesPimavanserin
go.drugbank.com/drugs/DB05316ApprovedInvestigational[L48241,A232573] Pimavanserin was also under review as a potential treatment for dementia-related psychosis; however, as of April 2021, FDA approval has not been granted for this indication despite previous … In fact, pimavanserin is the first antipsychotic drug without D<sub>2</sub> blocking activity.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin Receptor AntagonistsUndecylenic acid
go.drugbank.com/drugs/DB11117ApprovedUndecylenic acid was first isolated from the products of distillation of castor oil in 1877 via pyrolysis of ricinoleic acid, and has been polymerized for vinyl production [A32281]. … It is used as a precursor in the manufacture of aromatic chemicals, polymers or modified silicones [L1891].
Mixtures: NEOFUNGINA® POLVO, NEOFUNGINA® POLVOProducts: Hongocura M, Hongocura SQRX-411
go.drugbank.com/drugs/DB17868ExperimentalIt addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.
AstraZeneca COVID-19 Vaccine
go.drugbank.com/drugs/DB15656ApprovedInvestigationalclots in association with thrombocytopenia - a causal link with the vaccine has not been proven, but is possible and requires further analysis. … [L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another human coronavirus, Middle Eastern respiratory
Synonyms: ChAdOx-1-S[recombinant], ChAdOx1-S [recombinant]Peginterferon alfa-2b
go.drugbank.com/drugs/DB00022ApprovedInvestigationalWhen combined together, Peginterferon alfa-2b and [Ribavirin] have been shown to achieve a SVR between 41% for genotype 1 and 75% for genotypes 2-6 after 48 weeks of treatment. … The use of Peginterferon alfa-2b has largely declined since newer interferon-free antiviral therapies have been developed.
Synonyms: PEG-IFN-α-2b, Pegylated Interferon α-2bCategories: Hepatitis C, Interferon Type I