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Alfentanil
go.drugbank.com/drugs/DB00802ApprovedIllicitInvestigationalA short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. … Alfentanil is effective as an anesthetic during surgery, for supplementation of analgesia during surgical procedures, and as an analgesic for critically ill patients.
Categories: Fentanyl and fentanyl analoguesLiraglutide
go.drugbank.com/drugs/DB06655ApprovedInvestigationalVictoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist. … [Label,A6932] Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsNavitoclax
go.drugbank.com/drugs/DB12340InvestigationalIt blocks some of the enzymes that keep cancer cells from dying. … Navitoclax has been used in trials studying the treatment and basic science of Solid Tumors, Non-Hodgkin's Lymphoma, EGFR Activating Mutation, Chronic Lymphoid Leukemia, and Hematological Malignancies,
Categories: Antineoplastic and Immunomodulating AgentsPyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Categories: rifampicin, pyrazinamide and isoniazid, rifabutin, pyrazinamide and protionamideBenzphetamine
go.drugbank.com/drugs/DB00865ApprovedIllicit(From Martindale, The Extra Pharmacopoeia, 30th ed, p1222)
Fosamprenavir
go.drugbank.com/drugs/DB01319ApprovedInvestigationalFosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Categories: Amprenavir and ProdrugsImetelstat
go.drugbank.com/drugs/DB14909ApprovedInvestigationalcell morphology and a risk for transformation to acute myeloid leukemia. … Imetelstat is a first-in-class 18-amino acid oligonucleotide that directly and competitively inhibits human telomerase.
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesCyclandelate
go.drugbank.com/drugs/DB04838ApprovedWithdrawnIt may cause gastrointestinal distress and tachycardia. Cyclandelate is not approved for use in the U.S. or Canada, but is approved in various European countries.
Antrafenine
go.drugbank.com/drugs/DB01419ApprovedAntrafenine is a piperazine derivative drug that acts as an analgesic and anti-inflammatory drug with similar efficacy to naproxen. … It is not widely used as it has largely been replaced by newer drugs.
Benziodarone
go.drugbank.com/drugs/DB13277ApprovedWithdrawnIt was withdrawn from France markets and British markets due to its effects causing Jaundice in patients [T487, A175636]. … Benziodarone is a uricostatic and a uricosuric agent which is sold also under the name Amplivex-Labaz. It is used in the treatment of gout [A175630].