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Displaying results 4201 - 4210 of 10000 in total
  1. Drug

    Indenolol

    go.drugbank.com/drugs/DB08952
    ApprovedWithdrawn

    Indenolol is a drug of the beta-adrenergic blocker class.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  2. Drug

    Fentonium

    go.drugbank.com/drugs/DB08978
    ApprovedWithdrawn

    Fentonium is an atropine derivative.

  3. Drug

    Fendiline

    go.drugbank.com/drugs/DB08980
    ApprovedWithdrawn

    Fendiline is non-selective. … Fendiline is a coronary vasodilator which inhibits calcium function in muscle cells in excitation-contraction coupling. It has been proposed as an antiarrhythmic and antianginal agent.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SENSIT F
  4. Drug

    Enviomycin

    go.drugbank.com/drugs/DB08993
    Experimental

    It is isolated from an induced mutant of Streptomyces griseoverticillatus var. tuberacticus and acts as an antitubercular agent with less ototoxicity than tuberactinomycin.

    Synonyms: Tuberactinomycin N
  5. Drug

    Dexetimide

    go.drugbank.com/drugs/DB08997
    ApprovedWithdrawn

    A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Demexiptiline

    go.drugbank.com/drugs/DB08998
    Experimental

    Demexiptiline is marketed under the names Deparon or Tinoran. It is a tricyclic antidepressant which acts primarily as a norepinephrine reuptake inhibitor.

  7. Drug

    Carmofur

    go.drugbank.com/drugs/DB09010
    ApprovedWithdrawn

    Carmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Bromopride

    go.drugbank.com/drugs/DB09018
    Investigational

    Bromopride is a dopamine antagonist used as an antiemetic. Its prokinetic properties are similar to those of metoclopramide. It is unavailable in America or the United Kingdom.

    Mixtures: ENZYMED®TABLETAS RECUBIERTASSynonyms: 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
  9. Drug

    Vedolizumab

    go.drugbank.com/drugs/DB09033
    ApprovedInvestigational

    [A261576] Vedolizumab is administered by IV infusion over a period of 30 minutes; after the first dose, it is given again at two and six weeks and then every 8 weeks thereafter. … Vedolizumab is a recombinant humanized IgG1 monoclonal antibody directed against the human lymphocyte α4β7 integrin, a key mediator of gastrointestinal inflammation implicated in diseases like ulcerative

    Products: ENTYVIO SC, ENTYVIO® 108 MG SOLUCIÓN INYECTABLE
  10. Drug

    Pembrolizumab

    go.drugbank.com/drugs/DB09037
    ApprovedInvestigational

    Pembrolizumab is a highly selective IgG4-kappa humanized monoclonal antibody against PD-1 receptors. … It was generated by grafting the variable sequences of a very high-affinity mouse antihuman PD-1 antibody onto a human IgG4-kappa isotype containing a stabilizing S228P Fc mutation.

    Categories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsProducts: Keytruda Sc, KEYTRUDA SC