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Methylselenocysteine
go.drugbank.com/drugs/DB12697InvestigationalMethylselenocysteine has been used in trials studying the prevention of Prostate Carcinoma and No Evidence of Disease.
Synonyms: SE-METHYL-SELENO-L-CYSTEINECategories: Compounds used in a research, industrial, or household settingVelusetrag
go.drugbank.com/drugs/DB12702InvestigationalIt is a highly selective serotonin receptor agonist effective in patients with chronic constipation. It is being developed by Theravance. … Velusetrag was discovered by Theravance through the application of its multivalent drug design in a research program dedicated to finding new treatments for GI motility disorders.
Urokinase
go.drugbank.com/drugs/DB00013ApprovedInvestigationalWithdrawn[A191943] Urokinase remains connected between these 2 chains by a sulfhydryl bond.[A191943] Urokinase was granted FDA approval on 16 January 1978.[L12138]
Aldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalAldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. … Genetic engineering techniques were used to modify the human IL-2 gene, and the resulting expression clone encodes a modified human interleukin-2.
Synonyms: 125-L-Serine-2-133-interleukin 2, 125-L-serine-2-133-interleukin 2 (human reduced)Omalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigationalOmalizumab is a recombinant DNA-derived humanized monoclonal antibody directed against human immunoglobulin E (IgE). … [L50482] It is used to treat a range of immune and inflammatory conditions, including allergies, urticaria, and asthma.[A263507]
Somatotropin
go.drugbank.com/drugs/DB00052ApprovedInvestigational[A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa. … [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names.
Products: POLVO PARA RECONSTITUIR A SOLUCION INYECTABLE, SciTropin A Solution for Injection 5 mg/1.5 mlGemtuzumab ozogamicin
go.drugbank.com/drugs/DB00056ApprovedInvestigationalGemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora … On September 1 2017, gemtuzumab ozogamicin was again approved for the treatment of adults with newly diagnosed CD33-positive acute myeloid leukemia but with a lower dosing regimen and a different schedule
Indium In-111 satumomab pendetide
go.drugbank.com/drugs/DB00057ApprovedWithdrawnTumor associated glycoprotein (TAG) 72 (B72.3) monoclonal antibody conjugated with Indium 111 for radioimaging colon tumors. Satumomab Pendetide (trade name: OncoScint®) is no longer commercially available.
Pegaspargase
go.drugbank.com/drugs/DB00059ApprovedInvestigationalPegaspargase is a conjugate of monomethoxypolyethylene glycol (mPEG) and L-asparaginase (L-asparagine amidohydrolase), an asparagine-specific enzyme that converts L-asparagine into aspartic acid and ammonia … [A103,A255912,L44667] Pegaspargase has the same mechanism of action as [L-asparaginase] derived from _Escherichia coli_, a previously developed enzyme used for the treatment of acute lymphoblastic
Synonyms: PEG-L-Asparaginase, Peg/L-asparaginaseCategories: Compounds used in a research, industrial, or household settingInfliximab
go.drugbank.com/drugs/DB00065ApprovedInvestigationalInfliximab is a tumor necrosis factor (TNF-alpha or TNF-α) blocker and a chimeric monoclonal IgG1 antibody composed of human constant (75%) and murine variable (25%) regions [A31469]. … Inflectra, a first biosimilar drug product, was approved in 2016. In December 2017, Ixifi, a second biosimilar that was developed by Pfizer, was granted approval by the FDA.