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Displaying results 4241 - 4250 of 10000 in total
  1. Drug

    Enzalutamide

    go.drugbank.com/drugs/DB08899
    ApprovedInvestigational

    Enzalutamide is an androgen receptor (AR) inhibitor for the treatment of castration-resistant prostate cancer (CRPC), both metastatic and non-metastatic. … [L40639, A252667] Although androgen deprivation therapy (ADT) is the first-line treatment of prostate cancer and remission can be achieved, arising resistance is inevitable, becoming castration-resistant

    Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related AgentsProducts: SOFT CAPSULES 40MG, Xtandi 40mg Soft Capsules
  2. Drug

    Phenformin

    go.drugbank.com/drugs/DB00914
    ApprovedWithdrawn

    Although it is generally considered to be associated with an unacceptably high incidence of lactic acidosis, often fatal, it is still available in some countries. … A biguanide hypoglycemic agent with actions and uses similar to those of metformin.

    Categories: Drugs Used in Diabetes, Alimentary Tract and Metabolism
  3. Drug

    Miglustat

    go.drugbank.com/drugs/DB00419
    ApprovedInvestigational

    Miglustat was first developed as an anti-HIV agent in the 1990s. … It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric patients in the European Union, Brazil, and South Korea.

    Categories: Alimentary Tract and Metabolism, Various Alimentary Tract and Metabolism ProductsSynonyms: N-(n-Butyl)deoxynojirimycin, N-Butylmoranoline
  4. Drug

    Imiquimod

    go.drugbank.com/drugs/DB00724
    ApprovedInvestigational

    Imiquimod is an immune response modifier that acts as a toll-like receptor 7 agonist. Imiquimod is commonly used topically to treat warts on the skin of the genital and anal areas. … Miquimod is also used to treat a skin condition of the face and scalp called actinic keratoses and certain types of skin cancer called superficial basal cell carcinoma.

    International brands: You Care, Nan BoCategories: Skin and Mucous Membrane Agents
  5. Indication

    Community Acquired Pneumonia (CAP) caused by Escherichia Coli Infection

    go.drugbank.com/conditions/DBCOND0165526
    Drugs: Ceftobiprole medocaril
    Synonyms: Community Acquired Pneumonia (CAP) caused by Escherichia Coli Infection
  6. Indication

    Community Acquired Pneumonia (CAP) caused by Klebsiella Pneumoniae Infection

    go.drugbank.com/conditions/DBCOND0165527
    Drugs: Ceftobiprole medocaril
    Synonyms: Community Acquired Pneumonia (CAP) caused by Klebsiella Pneumoniae Infection
  7. Indication

    Community Acquired Pneumonia (CAP) caused by Streptococcus Pneumoniae Infections

    go.drugbank.com/conditions/DBCOND0165525
    Drugs: Ceftobiprole medocaril
    Synonyms: Community Acquired Pneumonia (CAP) caused by Streptococcus Pneumoniae Infections
  8. Drug

    Cefmetazole

    go.drugbank.com/drugs/DB00274
    Approved

    It has a high rate of efficacy in many types of infection and to date no severe side effects have been noted. … A semisynthetic cephamycin antibiotic with a broad spectrum of activity against both gram-positive and gram-negative microorganisms.

  9. Drug

    Dalfopristin

    go.drugbank.com/drugs/DB01764
    Approved

    Dalfopristin is a combination of two antibiotics (Dalfopristin and quinupristin) used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium. … Dalfopristin inhibits the early phase of protein synthesis in the bacterial ribosome and quinupristin inhibits the late phase of protein synthesis.

    Categories: Amino Acids, Peptides, and Proteins
  10. Drug

    Rivabazumab pegol

    go.drugbank.com/drugs/DB17788
    Investigational

    Rivabazumab pegol is being investigated as a treatment of Pseudomonas aeruginosa lung infections in patients with cystic fibrosis.[A259457]

    Synonyms: KB001-A (AN ANTI-PCRV PEGYLATED MONOCLONAL ANTIBODY FRAGMENT TO THE TYPE III SECRETION SYSTEM OF PSEUDOMONAS AERUGINOSA)