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TM5614
go.drugbank.com/drugs/DB16516InvestigationalTM5614 is a novel, orally active, plasminogen activator inhibitor 1 (PAI-1) inhibitor[A228788,A228793,]. PAI-1 is a marker of obesity, type 2 diabetes, and metabolic syndrome , and current studies are exploring downstream effects of its ...
Hesperetin
go.drugbank.com/drugs/DB01094InvestigationalHesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges.
SQ-109
go.drugbank.com/drugs/DB05186InvestigationalSQ-109 is an orally active, small molecule antibiotic for treatment of pulmonary TB. Currently in Phase I clinical trials, SQ-109 could replace one or more drugs in the current first-line TB drug regimen, simplify therapy, and shorten th...
Synonyms: N-adamantanyl-N'-geranyl-ethylenediamineRivoglitazone
go.drugbank.com/drugs/DB09200InvestigationalIt is being developed by Daiichi Sankyo Co.
Fosinoprilat
go.drugbank.com/drugs/DB14207ExperimentalFosinoprilat is the active phosphinic acid metabolite of prodrug [fosinopril], which is activated by esterases in vivo. It binds zinc with phosphinic acid group.
GLP-1 (7-36) amide
go.drugbank.com/drugs/DB19258InvestigationalGLP-1 (7-36) amide is under investigation in clinical trial NCT01185119 (Effect of GLP-1 on Glucose Metabolism in CNS Assessed by PET).
AG0302-COVID19
go.drugbank.com/drugs/DB16435InvestigationalSponsored by Anges, Inc. in Japan, the AG0302-COVID19 is a DNA-based vaccine that recently completed Phase I/II trials (NCT04527081)[A226813, L30548].
VAD-044
go.drugbank.com/drugs/DB17697InvestigationalVAD-044 is an allosteric AKT inhibitor developed by Vaderis Therapeutics AG. It is being investigated for the treatment of Hereditary Hemorrhagic Telangiectasia.[L46098]
Magnesium trisilicate
go.drugbank.com/drugs/DB09281ApprovedMagnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.