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Displaying results 4281 - 4290 of 10000 in total
  1. Drug

    Midomafetamine

    go.drugbank.com/drugs/DB01454
    IllicitInvestigational

    It is commonly referred to as MDMA or ecstasy. It is a widely abused drug classified as a hallucinogen and causes marked, long-lasting changes in brain serotonergic systems.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Serotonin Receptor Agonists
  2. Drug

    Chamaecyparis obtusa wood oil

    go.drugbank.com/drugs/DB14341
    Investigational

    Chamaecyparis obtusa wood oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Ste-medi
  3. Drug

    Imlunestrant

    go.drugbank.com/drugs/DB19043
    ApprovedInvestigational

    The FDA approved imlunestrant on September 25, 2025 [L54051] as a treatment for estrogen receptor (ER)-positive, HER2-negative, estrogen receptor 1 (ESR1)-mutated advanced or metastatic breast cancer with … [L54046] Imlunestrant works by antagonizing ER transcriptional activity and, by forming an unstable drug-receptor complex, promotes ER degradation via the ubiquitin-proteasome pathway.

    Categories: Estrogen Receptor Antagonists, Selective Estrogen Receptor Degraders
  4. Drug

    Desirudin

    go.drugbank.com/drugs/DB11095
    ApprovedWithdrawn

    It has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients.

  5. Drug

    8-chlorotheophylline

    go.drugbank.com/drugs/DB14132
    Experimental

    Because adenosine causes a decrease in neuronal firing, blockade of the adenosine receptor causes the reverse effect resulting in excitation. … a number of effects including nervousness, restlessness, insomnia, headache, and nausea, which are primarily attributed to its ability to block the adenosine receptor [A33889, A1539].

  6. Drug

    Quinaprilat

    go.drugbank.com/drugs/DB14217
    Experimental

    The active metabolite of the prodrug [quinapril].

    Categories: Agents Acting on the Renin-Angiotensin System
  7. Drug

    Carbopol 974P

    go.drugbank.com/drugs/DB05384
    ApprovedWithdrawn

    The compound, known as BufferGel, was in advanced clinical trials for its ability to prevent pregnancy, but was discontinued. … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.

  8. Drug

    Protionamide

    go.drugbank.com/drugs/DB12667
    ApprovedInvestigationalWithdrawn

    Prothionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.

  9. Target

    Transforming growth factor beta activator LRRC32

    go.drugbank.com/bio_entities/BE0014554
    TargetHumans

    Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19651619, PubMed:19750484, PubMed:22278742). As...

    Synonyms: Leucine-rich repeat-containing protein 32Function: receptor ligand inhibitor activity
  10. Drug

    Dihydromorphine

    go.drugbank.com/drugs/DB01565
    ExperimentalIllicit

    A semisynthetic analgesic used in the study of narcotic receptors. It has abuse potential. [PubChem]

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome