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GPI-1485
go.drugbank.com/drugs/DB05814InvestigationalGPI 1485 is being studied in phase 2 clinical trials for the treatment of Parkinson's disease and post-prostatectomy erectile dysfunction and in pre-clinical development for HIV related dementia and neuropathy … GPI 1485 is a product candidate that belongs to a class of small molecule compounds called neuroimmunophilin ligands.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsTM30339
go.drugbank.com/drugs/DB05085ExperimentalTM30339 thus imitates a natural mechanism, a satiety signal from the gastrointestinal system involved in the regulation of food intake in humans. TM30339 is developed for the treatment of obesity.
TA-CIN
go.drugbank.com/drugs/DB05809InvestigationalTA-CIN is a subunit vaccine comprising L2/E6/E7 proteins from Human Papillomavirus (HPV16), designed to generate a strong cellular immune response against HPV-infected cells.
Cipepofol
go.drugbank.com/drugs/DB16295ApprovedInvestigational[L63809] The drug has a longer regulatory history outside the United States: China's National Medical Products Administration approved it in December 2020 under the trade name Sishuning, and its Chinese … GABA-A receptors, similar to the previously approved [propofol].
Icosapent
go.drugbank.com/drugs/DB00159ApprovedInvestigationalNutraceutical-2 and prostaglandin-2 families. … It serves as the precursor for the prostaglandin-3 and thromboxane-3 families.
Mixtures: Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA, Animi-3 with Vitamin DCategories: Fatty Acids, Omega-3, Non COX-2 selective NSAIDSSildenafil
go.drugbank.com/drugs/DB00203ApprovedInvestigationalRegardless, sildenafil, among a variety of other similar or related PDE5 inhibitors, has become a common and effective treatment for erectile dysfunction and since its formal approval for medical use in … In eliciting its mechanism of action, sildenafil ultimately prevents or minimizes the breakdown of cyclic guanosine monophosphate (cGMP) by inhibiting cGMP specific phosphodiesterase type 5 (PDE5) [F3850
Mixtures: DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,6 FILM TABLETCategories: P-glycoprotein inhibitors, P-glycoprotein substratesAcalabrutinib
go.drugbank.com/drugs/DB11703ApprovedInvestigationalapproved under the FDA's accelerated approval pathway, which is based upon overall response rate and faciliates earlier approval of medicines that treat serious conditions or/and that fill an unmet medical … need based on a surrogate endpoint.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesProducts: CALQUENCE® 100MGDendritic cells vaccine
go.drugbank.com/drugs/DB15803InvestigationalWith a better safety profile than inactivated and live-attenuated virus and virus-vector vaccines, the recombinant chimeric DC vaccine reduces the risk of virulence recovery, pre-existing anti-vector immunity … The recombinant chimeric DC vaccine is a subunit-based vaccine candidate investigated for safety and effectiveness against SARS-CoV-2-induced pneumonia.
Calcium Phosphate
go.drugbank.com/drugs/DB11348ApprovedInvestigationalCalcium phosphate is typically available as an over the counter supplement, antacid, or as an added ingredient in some toothpastes [FDA Label] .
Mixtures: Taron-prex Prenatal, MULTIVIT M® CAPSULASCategories: ascorbic acid (vit C) and calcium, Compounds used in a research, industrial, or household settingSodium fluorophosphate
go.drugbank.com/drugs/DB09484ApprovedInvestigationalSodium monofluorophosphate is used in OTC dental preparations to help protect against cavities.
Mixtures: Univ of Vermont Medical Center Amenity, Ron 2Categories: Compounds used in a research, industrial, or household setting