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Mitomycin
go.drugbank.com/drugs/DB00305ApprovedInvestigationalTract Urothelial Cancer (LG-UTUC)[L12867] - as well as adjunctly to _ab externo_ glaucoma surgeries. … [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: MUTAMYCIN 20 MG, RIPTAM 20 MG POLVO LIOFILIZADOErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine has been shown to be safe and well tolerated in clinical trials. … Erdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent.
Categories: Heterocyclic Compounds, 1-RingProducts: ERDOSTIN 225 MG SAŞE, 20 ADET, ENZEVİN 300 MG KAPSÜL, 20 ADETMethylergometrine
go.drugbank.com/drugs/DB00353ApprovedInvestigationalA homolog of ergonovine containing one more CH2 group. (Merck Index, 11th ed)
Synonyms: D-lysergic acid 1-butanolamide, 9,10-Didehydro-N-[1-(hydroxymethyl)-propyl]-D-lysergamideInternational brands: Ingagen-M, Partan MValproic acid
go.drugbank.com/drugs/DB00313ApprovedInvestigationalIt first received approval on February 28, 1978 from the FDA under the trade name Depakene.[L6190] Since then, it has been investigated for neuroprotective, anti-manic, and anti-migraine effects. … [A178051] It enjoyed use as a popular organic solvent in industry and pharmaceutical manufacturing for nearly a century.
Synonyms: 2-Propylvaleric Acid, 2-propyl-pentanoic acidMixtures: PROKSIVAL XR 300 MG UZUN ETKILI FILM TABLET, 30 ADET, PROKSIVAL XR 300 MG UZUN ETKILI FILM TABLET, 30 ADETTopiramate
go.drugbank.com/drugs/DB00273ApprovedInvestigational[L10550] Characteristics that distinguish topiramate from other antiepileptic drugs are a monosaccharide chemical structure containing a sulfamate, and 40% of its mass accounted for by oxygen. … [A175249] It was initially approved by the FDA in 1996. In 2004, topiramate was approved for the prevention of migraine in adults.
Synonyms: 2,3:4,5-bis-O-(1-methylethylidene)-β-D-fructopyranose sulfamateProducts: AS-TOPIRAM 25 MG FILM TABLET, 60 ADET, AS-TOPIRAM 50 MG FILM TABLET, 60 ADETAcetylsalicylic acid
go.drugbank.com/drugs/DB00945ApprovedInvestigationalVet approvedThis drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. … Acetylsalicylic acid has both anti-inflammatory and antipyretic effects.
Synonyms: 2-Acetoxybenzoic acid, 2-Acetoxybenzenecarboxylic acidMixtures: Trinomia 100 mg/20 mg/10 mg Hartkapseln, THOMAPVRIN 250 mg/200 mg/50 mg TABLET, 10 ADETLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalDesiccated thyroid products contain a ratio of T4 to T3 of 4.2:1, which is significantly lower than the 14:1 ratio of secretion by the human thyroid gland. … [A179935] As a result, many cardiac functions including heart rate, cardiac output, and systemic vascular resistance are closely linked to thyroid status.
Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, SYNTHROID® 112 MCG TABLETASProducts: TİROSİNT 25 MCG/ML ORAL ÇÖZELTİ, 30 ADET, LEVOTIRON 200 MCG TABLET ,100 TABLETOfloxacin
go.drugbank.com/drugs/DB01165ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acidSertindole
go.drugbank.com/drugs/DB06144ApprovedWithdrawnIt has once again been approved and should soon be available on the French and Australian market. … It was first marketed in 1996 in several European countries before being withdrawn two years later because of numerous cardiac adverse effects.
Synonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-oneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDomperidone
go.drugbank.com/drugs/DB01184ApprovedInvestigationalVet approvedIt speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
Mixtures: RABELIS PLUS 20/10 MG KAPSUL, 30 ADET, RABELIS PLUS 20/30 MG MR KAPSUL, 30 ADETCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring