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Displaying results 4291 - 4300 of 10000 in total
  1. Drug

    Clomethiazole

    go.drugbank.com/drugs/DB06470
    Investigational

    It is a sedative and hypnotic that is widely used in treating and preventing symptoms of acute alcohol withdrawal. … It is also used for the management of agitation, restlessness, short-term insomnia and Parkinson's disease in the elderly.

    Categories: Compounds used in a research, industrial, or household setting
  2. Drug

    Allogeneic processed thymus tissue

    go.drugbank.com/drugs/DB16736
    Approved

    [A239814] On October 8, 2021, FDA approved allogeneic processed thymus tissue-agdc, under the market name RETHYMIC, as a one-time regenerative tissue-based therapy for immune reconstitution in pediatric … Allogeneic processed thymus tissue is used for immune reconstitution in immune disorders where the patients are severely immunocompromised due to the absence of a functional thymus, such as congenital

  3. Drug

    Amoxapine

    go.drugbank.com/drugs/DB00543
    Approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … In depressed individuals, amoxapine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.

  4. Drug

    Sodium stibogluconate

    go.drugbank.com/drugs/DB05630
    ApprovedInvestigational

    Sodium stibogluconate is sold in the UK as Pentostam (manufactured by GlaxoSmithKline). … Widespread resistance has limited the utility of sodium stibogluconate, and in many parts of the world, amphotericin or miltefosine are used instead.

  5. Drug

    Fruquintinib

    go.drugbank.com/drugs/DB11679
    ApprovedInvestigational

    This approval is based on favorable results obtained from the FRESCO and FRESCO-2 trials, where an increase in overall survival rate was observed in both trials.[L48791] … Although [bevacizumab] is successful in sustaining target inhibition, mandatory intravenous dosing, immunogenicity, and the potential to induce autoimmune diseases hinder its clinical application.

  6. Target

    Light-harvesting protein B-800/820 beta chain

    go.drugbank.com/bio_entities/BE0003922
    TargetRhodopseudomonas acidophila

    Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.

    Synonyms: LH3 complex subunit beta
  7. Drug

    Rose bengal I-131

    go.drugbank.com/drugs/DB09388
    Approved

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Raxibacumab

    go.drugbank.com/drugs/DB08902
    ApprovedInvestigational

    Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.

  9. Drug

    PF-03635659

    go.drugbank.com/drugs/DB12408
    Investigational

    Pf03635659 has been used in trials studying the treatment of Chronic Obstructive Pulmonary Disease.

    Categories: Receptor, Muscarinic M3, antagonists & inhibitors
  10. Drug

    Sugemalimab

    go.drugbank.com/drugs/DB16641
    ApprovedInvestigational

    [L32868] Sugemalimab was under investigation in the clinical trial NCT03802591 (A Study of CS1001 in Subjects With Gastric Adenocarcinoma or Gastro-esophageal Junction Adenocarcinoma). … [L32868, L32873, L53333] The antibody is produced in Chinese hamster ovary cells by recombinant DNA technology.