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Isosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Synonyms: D-Isosorbide dinitrateCategories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsBumetanide
go.drugbank.com/drugs/DB00887ApprovedInvestigationalBumetanide is a sulfamyl diuretic.
Synonyms: 3-(aminosulfonyl)-5-(butylamino)-4-phenoxybenzoic acid, 3-butylamino-4-(phenoxy)-5-sulfamoylbenzoic acidMixtures: BURINEX TABLET 1 mg, BURINEX TABLET 1 mgTestolactone
go.drugbank.com/drugs/DB00894ApprovedWithdrawnAn antineoplastic agent that is a derivative of progesterone and used to treat advanced breast cancer.
Synonyms: 13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone, 1-dehydrotestololactoneRimexolone
go.drugbank.com/drugs/DB00896ApprovedWithdrawnRimexolone is a 1% eye drop solution is a glucocorticoid steroid. It is used to treat inflammation in the eye. It is marketed as Vexol.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: VEXOL 5 ML OFTALMIK SOLUSYON, Vexol Ophthalmic Suspension - 1%Triazolam
go.drugbank.com/drugs/DB00897ApprovedInvestigationalInternationally, triazolam is a Schedule IV drug under the Convention on Psychotropic Substances.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingProducts: SOMESE® 0.25 MG TABLETAS, TRIALAM ® 0.25 MG/ TABLETATinidazole
go.drugbank.com/drugs/DB00911ApprovedInvestigationalA nitroimidazole antitrichomonal agent effective against _Trichomonas vaginalis_, _Entamoeba histolytica_, and _Giardia lamblia_ infections.
Synonyms: 1-(2-(Ethylsulfonyl)ethyl)-2-methyl-5-nitroimidazoleMixtures: GYNOMAX L VAJINAL OVUL, 7 ADET, GYNOMAX 100 MG/150 MG VAJINAL OVUL, 7 ADETRepaglinide
go.drugbank.com/drugs/DB00912ApprovedInvestigationalApproximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. … Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine.
Mixtures: REPAMEF 1/1000 MG EFERVESAN TABLET, 30 ADET, REPAMEF 1/500 MG EFERVESAN TABLET, 30 ADETCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingEnfuvirtide
go.drugbank.com/drugs/DB00109ApprovedInvestigationalEnfuvirtide is a 36 amino acid biomimetic peptide that is structurally similar to the HIV proteins that are responsible for the fusion of the virus to cell membranes and subsequent intracellular uptake … The first agent in the novel class of antiretroviral drugs called HIV fusion inhibitors, enfuvirtide works by inhibiting HIV-1 fusion with CD4 cells.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 SubstratesSpermine
go.drugbank.com/drugs/DB00127InvestigationalNutraceuticalSpermine is a spermidine-derived biogenic polyamine found as a polycation at all pH values. … Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Synonyms: N,N'-Bis(3-aminopropyl)-1,4-butanediamineAdenosine phosphate
go.drugbank.com/drugs/DB00131ApprovedInvestigationalNutraceuticalWithdrawnAdenosine phosphate, or adenylic acid, is an adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. … Adenosine phosphate was withdrawn by the FDA since it was considered neither safe nor effective for its intended uses as a vasodilator and an anti-inflammatory.[L43937]
Synonyms: Adenosine-5'P, 5'-O-PhosphonoadenosineInternational brands: My-B-Den