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Adenine
go.drugbank.com/drugs/DB00173ApprovedInvestigationalNutraceuticalA purine base and a fundamental unit of adenine nucleotides.
Mixtures: TERUFLEX Blood Bag System Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL Red Cell Preservative, TERUFLEX Blood Bag System with Blood Sampling Arm Anticoagulant Citrate Phosphate Dextrose (CPD) AND OPTISOL (AS-5) Red Cell PreservativeDolasetron
go.drugbank.com/drugs/DB00757ApprovedInvestigationalnausea and vomiting. … Dolasetron is an antinauseant and antiemetic agent indicated for the prevention of nausea and vomiting associated with moderately-emetogenic cancer chemotherapy and for the prevention of postoperative
Categories: Alimentary Tract and Metabolism, Antiemetics and AntinauseantsMK-8245
go.drugbank.com/drugs/DB13024InvestigationalMK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.
Talc
go.drugbank.com/drugs/DB09511ApprovedInvestigationalIn fact, recent studies have reported that talc increases the risk of ovarian and endometrial cancers by approximately 30 percent. … It is a substance often found in cosmetic and personal hygiene products including baby powder, adult body powders and facial powders.
Mixtures: Foot and Body PowderTebentafusp
go.drugbank.com/drugs/DB15283ApprovedInvestigationalThis approval marks the first bispecific T cell engager to be approved by the FDA to treat a solid tumour and being the first and only therapy for the treatment of unresectable or metastatic uveal melanoma … to be approved by the FDA.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsMetipranolol
go.drugbank.com/drugs/DB01214ApprovedWithdrawnA beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. It is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
Categories: Beta Blocking Agents and Thiazides, Antiglaucoma Preparations and MioticsPizotifen
go.drugbank.com/drugs/DB06153ApprovedSandomigran is available in a number of countries but is not approved by the FDA nor EMA. … It exhibits weak anticholinergic, antihistamine, and antikinin actions in addition to sedative and appetite-stimulating properties [L2292].
Toluene
go.drugbank.com/drugs/DB11558InvestigationalVet approvedIt is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.
Copanlisib
go.drugbank.com/drugs/DB12483ApprovedInvestigationalPI3K, a lipid kinase that activates downstream signalling pathways involved in cell survival and growth, that exists in different isoforms and is often overexpressed in hematological malignancies. … Copanlisib is a selective pan-Class I phosphoinositide 3-kinase (PI3K) inhibitor with preferential activity against the alpha and delta isoforms.
Categories: Antineoplastic and Immunomodulating AgentsPotassium cation
go.drugbank.com/drugs/DB01345ApprovedThe balance between potassium and sodium is maintained by ion pumps in the cell membrane. … The cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge.