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ZYCOV-D
go.drugbank.com/drugs/DB15892ExperimentalThe vaccine was developed using a DNA vaccine platform with a non-replicating and non-integrating plasmid carrying the gene of interest[L16503]. … The ZYCOV-D vaccine candidate was developed by Cadila Healthcare Ltd. based in India[A219758].
NV-5138
go.drugbank.com/drugs/DB19180InvestigationalNV-5138 is under investigation in clinical trial NCT06235905 (Open-label of SPN-820 in Adults With Major Depressive Disorder).
Von Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalIt was first approved by the FDA in 2015. … It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII).
Tesaglitazar
go.drugbank.com/drugs/DB06536InvestigationalTesaglitazar is a dual peroxisome proliferator-activated receptor alpha/gamma agonist which improves apolipoprotein levels in non-diabetic subjects with insulin resistance. … Tesaglitazar is a proposed treatment for type 2 diabetes and has completed several phase III clinical trials, however in May 2006 AstraZeneca announced that they had discontinued further development.
IGN101
go.drugbank.com/drugs/DB06500ExperimentalIGN101 is an antibody-based cancer vaccine directed against epithelial cancers. It consists of 500 ug 17-1A antibody adsorbed on aluminum hydroxide.
Tinoridine
go.drugbank.com/drugs/DB13001InvestigationalTinoridine is under investigation in clinical trial NCT01224756 (Efficacy of Tinoridine in Treating Pain and Inflammation in Adults).
Categories: Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-SteroidalSacubitril
go.drugbank.com/drugs/DB09292ApprovedInvestigationalIt was approved by the FDA after being given the status of priority review for on July 7, 2015.
Activated CDC42 kinase 1
go.drugbank.com/bio_entities/BE0000772TargetHumansNon-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation.
Synonyms: Tyrosine kinase non-receptor protein 2Pantetheinase
go.drugbank.com/bio_entities/BE0012284TargetEnzymeHumansAmidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine
Synonyms: Vascular non-inflammatory molecule 1Saccharomyces cerevisiae
go.drugbank.com/drugs/DB10447ApprovedSaccharomyces cerevisiae is a fungus which can provoke allergic reactions. Saccharomyces cerevisiae is used in allergenic testing.
Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Fungal Allergenic Extract