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Displaying results 431 - 440 of 10000 in total
  1. Drug

    Bivalirudin

    go.drugbank.com/drugs/DB00006
    ApprovedInvestigational

    Bivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin. … Once bound to the active site, thrombin cannot activate fibrinogen into fibrin, the crucial step in the formation of thrombus. It is administered intravenously.

    Products: OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 10 ADET, Bivalirudin Accord 250 mg Pulver für ein Konzentrat zur Herstellung einer Injektions-/Infusionslösung
  2. Pathway

    Acylcarnitine (4Z,7Z,10S,11E)-10-hydroperoxy-12-[(1R,4S,5S,6R)-6-[(2Z)-pent-2-en-1-yl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl]dodeca-4,7,11-trienoylcarnitine

    smpdb.ca/view/SMP0123477
    Metabolic

    (4Z,7Z,10S,11E)-10-hydroperoxy-12-[(1R,4S,5S,6R)-6-[(2Z)-pent-2-en-1-yl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl]dodeca-4,7,11-trienoylcarnitine is an acylcarnitine. … form (4Z,7Z,10S,11E)-10-hydroperoxy-12-[(1R,4S,5S,6R)-6-[(2Z)-pent-2-en-1-yl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl]dodeca-4,7,11-trienoylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  3. Drug

    Epinephrine

    go.drugbank.com/drugs/DB00668
    ApprovedInvestigationalVet approved

    On August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353]. … Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA.

    Mixtures: ULTRAVER D-S 80 MG + 0,01819 MG / 2 ML ENJEKSİYONLUK ÇÖZELTİ, 20 ADET, LIDOCAINA 2% E-80 CON EPINEFRINA 1:80000Categories: Sympathomimetics in Glaucoma Therapy
  4. Drug

    Eslicarbazepine acetate

    go.drugbank.com/drugs/DB09119
    ApprovedInvestigational

    Eslicarbazepine acetate (ESL) is an anticonvulsant medication approved for use in Europe, the United States and Canada as an adjunctive therapy for partial-onset seizures that are not adequately controlled … Eslicarbazepine acetate is marketed as Aptiom in North America and Zebinix or Exalief in Europe. It is available in 200, 400, 600, or 800mg tablets that are taken once daily, with or without food.

    Synonyms: (10S)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide, (10S)-5-carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetateProducts: Eslibon 800 mg-Tabletten, Eslibon 200 mg-Tabletten
  5. Drug

    Levetiracetam

    go.drugbank.com/drugs/DB01202
    ApprovedInvestigational

    It was first approved for use in the United States in 1999 and is structurally and mechanistically unrelated to other anti-epileptic drugs (AEDs). … interactions[L8606,L8600,L8615] - these characteristics make it a desirable choice over other AEDs, a class of drugs notorious for having generally narrow therapeutic indexes and a propensity for involvement in

    Products: LEV-END 250 MG FILM KAPLI TABLET, 50 ADET, LEV-END 500 MG FILM KAPLI TABLET, 50 ADET
  6. Drug

    Domperidone

    go.drugbank.com/drugs/DB01184
    ApprovedInvestigationalVet approved

    It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

    Mixtures: DEXGARD 30/30 MG MR KAPSUL, 60 ADET, DEXRIDON MR 30/10 MG KAPSÜL ,30 KAPSÜLProducts: DOMPERIDONE EG, DIGESPAR 10 MG
  7. Drug

    Topotecan

    go.drugbank.com/drugs/DB01030
    ApprovedInvestigational

    An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA topoisomerases, type I.

    Synonyms: 9-[(dimethylamino)methyl]-10-hydroxy-(4S)-camptothecinProducts: Topotecan Hikma 1 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Topotecan Hikma 4 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  8. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.

    International brands: Felodur ER, Plendil ERMixtures: DELIX DUO 2.5 MG/2.5 MG TABLET, 30 ADET, DELIX DUO 5 MG/5 MG FİLM KAPLI TABLET, 30 ADET
  9. Drug

    Bilastine

    go.drugbank.com/drugs/DB11591
    Approved

    Bilastine is a novel new-generation antihistamine that is highly selective for the H1 histamine receptor, has a rapid onset and prolonged duration of action.

    Products: BILASTINA EG, ELHIST ® 20 MG
  10. Indication

    LDL > 190 mg/dl after diet modification

    go.drugbank.com/conditions/DBCOND0119340
    Drugs: Lovastatin · Pravastatin
    Synonyms: LDL > 190 mg/dl after diet modification