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Displaying results 431 - 440 of 1342 in total
  1. Drug

    Tirasemtiv

    go.drugbank.com/drugs/DB12209
    Investigational

    Tirasemtiv has been used in trials studying the treatment of Myasthenia Gravis, Intermittent Claudication, and Amyotrophic Lateral Sclerosis.

  2. Drug

    Teglarinad chloride

    go.drugbank.com/drugs/DB05217
    Investigational

    Although the exact mechanism of action has yet to be fully elucidated, GMX1778 appears to antagonize nuclear factor-kappa B (NF-kB) transcription, resulting in the induction of tumor cell apoptosis.

  3. Drug

    Racepinephrine

    go.drugbank.com/drugs/DB11124
    Approved

    Racepinephrine is a racemic mixture consisting of d-DB00668 and l-DB00668 enantiomers. Epinephrine is a non-selective α- and β-adrenergic receptor agonist. It is a bronchodilator used in the temporary relief of mild symptoms of intermitt...

    Mixtures: Sil Trax Plus No 8, Sil Trax Plus No 9Products: Sil Trax Epi No 8, Sil Trax Epi No 9
  4. Drug

    Gefurulimab

    go.drugbank.com/drugs/DB18928
    Investigational

    Gefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).

  5. Drug

    Indapamide

    go.drugbank.com/drugs/DB00808
    ApprovedInvestigational

    The most significant modifiable risk factor for cardiovascular disease and the most prominent contributor to all-cause mortality is hypertension. … hypertension should include a number of lifestyle changes (ie. reduced sodium intake) along with pharmacotherapy - it should be noted that treatment with several antihypertensive agents may be required in order

  6. Drug

    Crotamiton

    go.drugbank.com/drugs/DB00265
    Approved

    It is a colorless to slightly yellowish oil, having a faint amine-like odor. It is miscible with alcohol and with methanol.

  7. Drug

    Biperiden

    go.drugbank.com/drugs/DB00810
    ApprovedInvestigationalWithdrawn

    A muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapy...

  8. Drug

    Autologous Hematopoietic Peripheral Blood Stem Cells

    go.drugbank.com/drugs/DB17067
    Investigational

    Autologous hematopoietic peripheral blood stem cells were tested in a clinical trial (NCT00424489) by Northwestern University for the treatment of refractory myasthenia gravis.

  9. Drug

    Brinzolamide

    go.drugbank.com/drugs/DB01194
    Approved

    Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase II (CA-II) inhibitor indicated to reduce ocular pressure in patients with ocular hypertension or open-angle glaucoma. Although the exact pathophysiology of...

  10. Drug

    Bupivacaine

    go.drugbank.com/drugs/DB00297
    ApprovedInvestigational

    Bupivacaine is a widely used local anesthetic agent.