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Displaying results 4391 - 4400 of 5895 in total
  1. Drug

    Fimasartan

    go.drugbank.com/drugs/DB09279
    Investigational

    It has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials.

  2. Drug

    Amcipatricin

    go.drugbank.com/drugs/DB12333
    Investigational

    In preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp. … SPK-843 doses of higher than 1.0 mg/kg of body weight exhibit no renal toxicities and a tendency toward better survival prolongation than the estimated maximum tolerated doses of amphotericin B (Fungizone

  3. Drug

    Ulotaront

    go.drugbank.com/drugs/DB15665
    Investigational

    Additional clinical trials of SEP-363856 are required to confirm the safety and efficacy of this drug.[A193506] … Negative symptoms of schizophrenia are more difficult to treat and may include flattened affect, anhedonia, and social withdrawal.

  4. Drug

    Ranirestat

    go.drugbank.com/drugs/DB05327
    Investigational

    It has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.

  5. Drug

    Mequitazine

    go.drugbank.com/drugs/DB01071
    Investigational

    It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.

  6. Drug

    Poliglusam

    go.drugbank.com/drugs/DB11234
    ApprovedInvestigational

    It is also reported to have an effect on protein aggregation, emulsification capacity, film-forming ability, clarifying ability, and fatty acid absorption capability [L999].

  7. Drug

    Oxitriptan

    go.drugbank.com/drugs/DB02959
    ApprovedInvestigationalNutraceuticalWithdrawn

    More study is needed to determine efficacy in treating depression.

  8. Drug

    MF101

    go.drugbank.com/drugs/DB05052
    Investigational

    MF101 is a novel estrogen receptor beta (ERβ) selective agonist and unlike currently available hormone therapies, does not activate the estrogen receptor alpha (ERα), known to be implicated in tumor formation

  9. Drug

    CP-122721

    go.drugbank.com/drugs/DB05421
    Experimental

    CP-122721, neurokinin 1 (NK1) antagonist is developed by Pfizer to treat depression, emesis, and inflammatory diseases including asthma and irritable bowel syndrome.

  10. Drug

    PF-03382792

    go.drugbank.com/drugs/DB12949
    Investigational

    Pf 03382792 is under investigation in clinical trial NCT01045863 (To Evaluate Safety, Tolerability, Plasma Drug Levels And Other Biological Effects In Healthy Volunteers).