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Rademikibart
go.drugbank.com/drugs/DB18995InvestigationalRademikibart is under investigation in clinical trial NCT04773678 (Efficacy and Safety of CBP-201 in Patients With Moderate to Severe Persistent Asthma With Type 2 Inflammation).
Claseprubart
go.drugbank.com/drugs/DB22867InvestigationalClaseprubart is under investigation in clinical trial NCT06858579 (A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)).
Melitracen
go.drugbank.com/drugs/DB13384InvestigationalCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeFimasartan
go.drugbank.com/drugs/DB09279InvestigationalIt has been found to be safe when administered with hydrochlorothiazide (a diuretic) in clinical trials.
Amcipatricin
go.drugbank.com/drugs/DB12333InvestigationalIn preclinical models, SPK-843 shows in vitro inhibitory activity comparable to or better than that of Amphotericin B against Candida spp., Cryptococcus neoformans, and Aspergillus spp. … SPK-843 doses of higher than 1.0 mg/kg of body weight exhibit no renal toxicities and a tendency toward better survival prolongation than the estimated maximum tolerated doses of amphotericin B (Fungizone
Ulotaront
go.drugbank.com/drugs/DB15665InvestigationalAdditional clinical trials of SEP-363856 are required to confirm the safety and efficacy of this drug.[A193506] … Negative symptoms of schizophrenia are more difficult to treat and may include flattened affect, anhedonia, and social withdrawal.
Ranirestat
go.drugbank.com/drugs/DB05327InvestigationalIt has been used in trials studying the treatment of Mild to Moderate Diabetic Sensorimotor Polyneuropathy.
Mequitazine
go.drugbank.com/drugs/DB01071InvestigationalIt provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Poliglusam
go.drugbank.com/drugs/DB11234ApprovedInvestigationalIt is also reported to have an effect on protein aggregation, emulsification capacity, film-forming ability, clarifying ability, and fatty acid absorption capability [L999].
Oxitriptan
go.drugbank.com/drugs/DB02959ApprovedInvestigationalNutraceuticalWithdrawnMore study is needed to determine efficacy in treating depression.