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Displaying results 4391 - 4400 of 8700 in total
  1. Pathway

    Felodipine Action Pathway

    smpdb.ca/view/SMP0000377
    Drug action

    Felodipine may be used to treat mild to moderate essential hypertension. .

    Drugs: ATP · Felodipine · Potassium cation · Calcium
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  2. Pathway

    Isradipine Action Pathway

    smpdb.ca/view/SMP0000378
    Drug action

    Isradipine (also known as DynaCirc or Prescal) is a calcium channel blocker within dihydropyridine (DHP) class that can be used for treating high blood pressure and essential hypertension. There are at least 5 different types of calcium ...

    Drugs: ATP · Isradipine · Potassium cation · Calcium
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  3. Pathway

    Bopindolol Action Pathway

    smpdb.ca/view/SMP0000657
    Drug action

    Adrenaline (also known as epinephrine) can activate β1 adrenergic receptor so that the heart rate and output will be increased. … Bopindolol (also known as Sandonorm) is a selective β1 adrenergic receptor antagonist (beta blocker), which can be used for treatment of high blood pressure (hypertension) and irregular heartbeats

    Drugs: ATP · Potassium cation · Calcium · Bopindolol
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  4. Pathway

    Sotalol Action Pathway

    smpdb.ca/view/SMP0000660
    Drug action

    Sotalol is a beta-adrenergic receptor antagonist, which is a treatment regimen for heart failure such as abnormal heart rhythms. … The electrophysiologic effects of sotalol may be due to its selective inhibition of the rapidly activating component of the potassium channel involved in the repolarization of cardiac cells.

    Drugs: ATP · Sotalol · Potassium cation · Calcium
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  5. Pathway

    Epinephrine Action Pathway

    smpdb.ca/view/SMP0000661
    Drug action

    Epinephrine can be derived from phenylalanine and tyrosine and it is an active sympathomimetic hormone that can be secreted from adrenal medulla. Epinephrine can stimulate alpha- and beta- adrenergic systems by binding on alpha-1 and bet...

    Drugs: ATP · Epinephrine · Potassium cation · Calcium
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  6. Pathway

    Isoprenaline Action Pathway

    smpdb.ca/view/SMP0000663
    Drug action

    Isoprenaline can bind and inhibit beta-1 adrenergic receptor on both vascular smooth muscle, which lead to inhibition of vasoconstriction in peripheral blood vessels and adrenergic stimulation of endothelial

    Drugs: ATP · Isoprenaline · Potassium cation · Calcium
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  7. Pathway

    Arbutamine Action Pathway

    smpdb.ca/view/SMP0000664
    Drug action

    Arbutamine is a synthetic catecholamine used to initiate a cardiac stress response to mimic exercise to detect coronary artery disease. Arbutamine has nonselective beta and weak alpha-1-adrenergic activity which causes increased chronotr...

    Drugs: ATP · Arbutamine · Potassium cation · Calcium
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  8. Pathway

    Bevantolol Action Pathway

    smpdb.ca/view/SMP0000668
    Drug action

    Bevantolol hydrocholride, also known as bevantolol, is a cardioselective beta blocker prescribed to treat angina pectoris and hypertension. Bevantolol is an antagonist of beta-1 adrenoreceptors to block the G protein signalling cascade a...

    Drugs: ATP · Bevantolol · Potassium cation · Calcium
    Enzymes: Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase, Ryanodine receptor 2
  9. Drug

    Zinc cation

    go.drugbank.com/drugs/DB14532
    Investigational

    Mixtures: Orajel 4X Medicated PM For Toothache and Gum, Orajel 4X Medicated For Toothache and Gum
  10. Drug

    Clobetasol

    go.drugbank.com/drugs/DB11750
    ApprovedInvestigationalWithdrawn

    Clobetasol is under investigation for the treatment of Scleroderma. Clobetasol has been investigated for the prevention of Psoriasis and Cutaneous Atrophy Due to Corticosteroids.

    Categories: Corticosteroid Hormone Receptor Agonists, Cytochrome P-450 Substrates