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Cilazapril
go.drugbank.com/drugs/DB01340ApprovedInvestigationalIt belongs to the angiotensin-converting enzyme inhibitors (ACE inhibitors) class of drugs. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat.
Products: Co CilazaprilSodium copper chlorophyllin
go.drugbank.com/drugs/DB16522InvestigationalSCC of the commercial-grade is prepared from a reaction between a crude chlorophyll extract and methanolic sodium hydroxide, followed by replacement of the central magnesium atom with a heavy metal[A227718 … Sodium copper chlorophyllin (SCC) is a water-soluble and bright green mixture derived from natural chlorophyll that has potential antimutagenic and antioxidant properties[A227718].
Cyclic GMP
go.drugbank.com/drugs/DB02315ExperimentalIts levels increase in response to a variety of hormones, including acetylcholine, insulin, and oxytocin and it has been found to activate specific protein kinases. (From Merck Index, 11th ed) … Cyclic guanosine monophosphate (Cyclic GMP) is a guanine nucleotide containing one phosphate group which is esterified to the sugar moiety in both the 3'- and 5'-positions.
Fasinumab
go.drugbank.com/drugs/DB12157Investigational[A241165] NGF was first discovered in the 1950s[A241180] and was the first neurotrophic factor to be identified and biochemically characterized. … It is currently under investigation for the treatment osteoarthritic pain[A241045] and has demonstrated significantly greater pain relief and functional improvement as compared to standard therapy (i.e
AV-COVID-19
go.drugbank.com/drugs/DB15802InvestigationalThe vaccine is created from the receiving patients’ isolated peripheral blood monocytes. … The vaccine was developed and tested by Aivita Biomedical, Inc.. As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.
Alfentanil
go.drugbank.com/drugs/DB00802ApprovedIllicitInvestigationalA short-acting opioid anesthetic and analgesic derivative of fentanyl. It produces an early peak analgesic effect and fast recovery of consciousness. Alfentanil is effective as an anesthetic during surgery, for supplementation of analges...
Synonyms: N-(1-(2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl)-4-(methoxymethyl)-4-piperidyl)propionanilideCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePerospirone
go.drugbank.com/drugs/DB08922InvestigationalIt is also shown to be less associated with extrapyramidal symptoms as a side effect compared to [DB00502]. … It is commonly present as the hydrated hydrochloride salt form.
Synonyms: cis-N-(4-(4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl)butyl)-1,2-cyclohexanedicarboximideCry5B
go.drugbank.com/drugs/DB17783ExperimentalCry5B is a pore-forming crystal protein produced by and derived from the soil bacterium _Bacillus thuringiensis_.
COVID-19 convalescent plasma
go.drugbank.com/drugs/DB15692Investigational[L14333] Although there are no formal clinical trial results for the safety or efficacy of COVID-19 convalescent plasma, early results from 5000 patients under the FDA expanded access program suggest … COVID-19 convalescent plasma is plasma collected from patients who have acquired and subsequently recovered from COVID-19 and which contains antibodies against the causative agent SARS-CoV-2.
Multipotent adult arogenitor cells
go.drugbank.com/drugs/DB15742InvestigationalThe cells for creation of the product are isolated from a qualified donor and expanded on a large scale and then frozen until use. After administration, the cells are cleared from the body over time. … Like mesenchymal stem cells, MAPCs are derived from bone-marrow stroma and are non-hematopoietically adherent.