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Cannabidivarin
go.drugbank.com/drugs/DB14050InvestigationalIn October 2017 CBDV was given orphan designation by the European Medicines Agency for use in Rett Syndrome [L2952] and again in February 2018 for treatment of Fragile X Syndrome [L2951]. … The anti-epileptic activity of CBD and CBDV is thought to be modulated by their effects on transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor
Synonyms: 2-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-5-propylbenzene-1,3-diol, CBD-VCobamamide
go.drugbank.com/drugs/DB11191ApprovedNutraceuticalCobamamide is one of the active forms of vitamin B12 that is also known as _adenosylcobalamin_ or _dibencozide_. … This drug is available as a nutritional supplement to prevent vitamin B12 deficiency. Vitamin B12 is a collective term for these variously substituted corrinoids.
Synonyms: 5'-Deoxy-5'-adenosylcobalamin, Coenzyme B-12Categories: Vitamin B Complex, Heterocyclic Compounds, 1-RingLumefantrine co-artemether
go.drugbank.com/drugs/DB13085ApprovedInvestigationalWithdrawnThe exact mechanism of action of lumefantrine is not well defined, but it is thought to inhibit -hematin formation, an important detoxification pathway for the parasite. … falciparum malaria that is resistant to other antimalarials.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTheobromine
go.drugbank.com/drugs/DB01412InvestigationalTheobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. … It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalAlendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Synonyms: (4-amino-1-hydroxybutylidene)bisphosphonic acid, 4-amino-1-hydroxybutane-1,1-diphosphonic acidMixtures: ALENDRONATO E COLECALCIFEROLO PENSA, ALENDRONATO E COLECALCIFEROLO PENSAOxycodegol
go.drugbank.com/drugs/DB14146InvestigationalThe lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class [A33997, A34016]. … This is also thought to be the reason behind the reduced frequency of CNS-mediated adverse effects, like sedation, seen with Loxicodegol.
Categories: Heterocyclic Compounds with 4 or More RingsRufinamide
go.drugbank.com/drugs/DB06201ApprovedRufinamide is a triazole derivative and an anticonvulsant medication to treat seizure disorders like Lennox-Gastuat syndrome, a form of childhood epilepsy. … Clinical trials suggest its efficacy in the treatment of partial seizures.
Categories: Cytochrome P-450 CYP3A Inducers, Heterocyclic Compounds, 1-RingProducts: INOVELON® 400 MGSolenopsis richteri
go.drugbank.com/drugs/DB11026ApprovedSolenopsis richteri allergenic extract is used in allergenic testing. It is extracted from the black imported fire ant which is native to South Amercia. … The species has also been introduced in North Amercia. When stung, the bites are characterized by sterile pustules that are surrounded by reddened swelling along with redness extending beyond.
Stanolone
go.drugbank.com/drugs/DB02901IllicitInvestigationalUnlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid. … A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone.
Synonyms: 4-Dihydrotestosterone, 17beta-Hydroxyandrostan-3-oneCategories: Sex Hormones and Modulators of the Genital System, 5-Androstanon (3) Derivatives