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Didanosine
go.drugbank.com/drugs/DB00900ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen. … Didanosine is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA by binding to reverse transcriptase; ddI is then metabolized to dideoxyadenosine triphosphate, its putative
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2',3'-dideoxyinosine, 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-oneOndansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawnA competitive serotonin type 3 receptor antagonist. … [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: BRYTEROL® TABLETAS X 8 MG, ZOPHRALEN 4 MG/2 ML IV AMPUL, 5 ADETQuinidine
go.drugbank.com/drugs/DB00908ApprovedQuinidine is a D-isomer of [quinine] present in the bark of the Cinchona tree and similar plant species. … This alkaloid was first described in 1848 and has a long history as an antiarrhythmic medication.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic IndexSynonyms: (R)-(6-Methoxyquinolin-4-yl)((3S,4R,7S)-3-vinylquinuclidin-7-yl)methanol, (S)-(6-Methoxy-quinolin-4-yl)-((2R,5R)-5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanolAbacavir
go.drugbank.com/drugs/DB01048ApprovedInvestigationalAbacavir (ABC) is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. … Chemically, it is a synthetic carbocyclic nucleoside and is the enantiomer with 1S, 4R absolute configuration on the cyclopentene ring.
Mixtures: N/A, TOLAMID®Categories: Heterocyclic Compounds, 2-RingAtorvastatin
go.drugbank.com/drugs/DB01076ApprovedInvestigationalAtorvastatin (Lipitor®), is a lipid-lowering drug included in the statin class of medications. … the number of major cardiovascular events (heart attack, stroke, coronary revascularization, and coronary death) for every 1 mmol/L reduction in LDL without any significant side effects or risks.
Mixtures: ./5 มก./5 มก., TIAZOMET ® A 40/10 TABLETASCategories: P-glycoprotein inhibitors, P-glycoprotein substratesLevocabastine
go.drugbank.com/drugs/DB01106ApprovedLevocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.
Categories: Heterocyclic Compounds, 1-RingFlavoxate
go.drugbank.com/drugs/DB01148ApprovedA drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear. … It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem]
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2-(1-piperidinyl)ethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate, 2-piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-1-benzopyran-8-carboxylateProcaterol
go.drugbank.com/drugs/DB01366ApprovedWithdrawnA long-acting beta-2-adrenergic receptor agonist. It is a potent bronchodilator that may be administered orally or by aerosol inhalation.
Categories: Adrenergic beta-2 Receptor Agonists, Heterocyclic Compounds, 2-RingGinseng
go.drugbank.com/drugs/DB01404ApprovedInvestigationalNutraceuticalGinseng is promoted as an adaptogen (a product that increases the body's resistance to stress), one which can to a certain extent be supported with reference to its anticarcinogenic and antioxidant properties
Mixtures: BEDOYECTA + G, GINSENG-E CAPSULEProducts: Dendropanax MCefpodoxime
go.drugbank.com/drugs/DB01416ApprovedInvestigationalVet approvedCommonly used to treat acute otitis media, pharyngitis, and sinusitis, cefpodoxime proxetil is a prodrug which is absorbed and de-esterified by the intestinal mucosa to Cefpodoxime.
Mixtures: INFEX PLUS 100/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 ML, INFEX PLUS 40/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 MLCategories: Heterocyclic Compounds, 2-Ring