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Displaying results 4441 - 4450 of 10000 in total
  1. Drug

    DG051

    go.drugbank.com/drugs/DB05177
    Experimental

    DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack. … DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a potent promoter of inflammation.

  2. Drug

    Egtazic acid

    go.drugbank.com/drugs/DB19986
    Experimental

    Egtazic acid is a small molecule drug. Egtazic acid has a monoisotopic molecular weight of 380.14 Da.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Valinomycin

    go.drugbank.com/drugs/DB14057
    Experimental

    (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies. … It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring.

    Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsSynonyms: Potassium ionophore I
  4. Drug

    Tipranavir

    go.drugbank.com/drugs/DB00932
    ApprovedInvestigational

    Tipranavir is a sulfonamide-containing dyhydropyrone and a nonpeptidic protease inhibitor that targets the HIV protease. Tipranavir and ritonavir are coadministered to treat HIV.

    Categories: P-glycoprotein inducers, P-glycoprotein inhibitors
  5. Drug

    16-Bromoepiandrosterone

    go.drugbank.com/drugs/DB05107
    Investigational

    It is a chemical relative of DHEA which was selected for development after it showed antiretroviral activity in laboratory tests. … 16-Bromoepiandrosterone is an injectable formulation of a compound called alpha-epi-bromide.

  6. Drug

    Bacillus calmette-guerin substrain connaught live antigen

    go.drugbank.com/drugs/DB10804
    ApprovedInvestigationalWithdrawn

    Bacillus calmette-guerin substrain connaught live antigen is intravesically administered for the treatment and prophylaxis of carcinoma in situ (CIS) of the urinary bladder and for the prophylaxis of primary … It is prepared from the Connaught strain of Bacillus Calmette and Guérin.

  7. Drug

    VIT-100

    go.drugbank.com/drugs/DB05865
    Experimental

    It is believed that similar effects would be seen in cells isolated from hypertrophic scars. … In preclinical studies, companyl has shown that VIT-100 inhibits the growth of cells taken from multiple keloid biopsies as compared to the same keloidal cells treated with a control.

  8. Drug

    Roxatidine acetate

    go.drugbank.com/drugs/DB08806
    Investigational

    Roxatidine acetate is a specific and competitive H2 receptor antagonist. It is currently approved in South Africa under the tradename Roxit.

    Categories: Heterocyclic Compounds, 1-RingProducts: NEOH 2
  9. Drug

    Tosylchloramide

    go.drugbank.com/drugs/DB14708
    Investigational

    Tosylchloramide, also known as chloramine-T, is a chlorinated and deprotonated sulfonamide used as a mild disinfectant. It is not stable in the water dissolved form.

    Salts: Chloramine-T, Chloramine-T trihydrateCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Tacrine

    go.drugbank.com/drugs/DB00382
    ApprovedWithdrawn

    A centerally active cholinesterase inhibitor that has been used to counter the effects of muscle relaxants, as a respiratory stimulant, and in the treatment of Alzheimer's disease and other central nervous

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesSynonyms: 1,2,3,4-tetrahydro-9-acridinamine, 1,2,3,4-tetrahydro-9-aminoacridine