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Displaying results 4441 - 4450 of 10000 in total
  1. Drug

    Metoclopramide

    go.drugbank.com/drugs/DB01233
    ApprovedInvestigational

    Diabetic gastroparesis is a condition that causes frequent nausea and vomiting, which has a negative impact on quality of life and poses a significant burden on the healthcare system. … [A184934] Metoclopramide is a dopamine antagonist used to treat nausea and vomiting that may be associated with diabetic gastroparesis in addition to gastroesophageal reflux disease (GERD).

    Synonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideMixtures: CLIFAR® GOTAS, PLASIL®ENZIMATICO
  2. Drug

    Levodopa

    go.drugbank.com/drugs/DB01235
    ApprovedInvestigational

    Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after … Levodopa is a prodrug of dopamine that is administered to patients with Parkinson's due to its ability to cross the blood-brain barrier[Label].

    Synonyms: 3-Hydroxy-L-tyrosine, (−)-3-(3,4-dihydroxyphenyl)-L-alanineMixtures: SR Tablet 50/200, DOPADEX SR 50 MG/200 MG UZATILMIŞ SALIMLI TABLET,30 ADET
  3. Drug

    Sevoflurane

    go.drugbank.com/drugs/DB01236
    ApprovedInvestigationalVet approved

    [L42340] It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. … Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia.

    Synonyms: 1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propaneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates
  4. Drug

    Bromodiphenhydramine

    go.drugbank.com/drugs/DB01237
    Approved

    Bromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies.

    Synonyms: 2-(p-bromo-α-phenylbenzyloxy)-N,N-dimethylethylamine, β-(p-bromobenzhydryloxy)ethyldimethylamine
  5. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.

    Synonyms: Prostaglandin X, (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acidCategories: Prostaglandins I
  6. Drug

    Decamethonium

    go.drugbank.com/drugs/DB01245
    Approved

    Decamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. … It is similar to acetylcholine and acts as a partial agonist of the nicotinic acetylcholine receptor.

    Synonyms: N,N,N,N',N',N'-hexamethyl-1,10-decanediaminium
  7. Drug

    Gliquidone

    go.drugbank.com/drugs/DB01251
    Approved

    Gliquidone is a sulfonylurea drug used to treat diabetes mellitus type 2. It is an ATP-dependent K+ (KATP) channel blocker. … This block causes a depolarization which leads to activation of voltage-dependent Ca channels and Ca2+ influx, and eventually increases insulin release.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  8. Drug

    Sitagliptin

    go.drugbank.com/drugs/DB01261
    ApprovedInvestigational

    Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus[FDA label,A2260,A2255,A2256

    Mixtures: ARGLIPTIN-D, SIPTATINMET RCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  9. Drug

    Carbetocin

    go.drugbank.com/drugs/DB01282
    ApprovedInvestigational

    Carbetocin is a drug used to control postpartum hemorrhage, bleeding after giving birth. … It is an analogue of oxytocin, and its action is similar to that of oxytocin -- it causes contraction of the uterus.

    Synonyms: 1-butanoic acid-2-(O-methyl-L-tyrosine)-1-carbaoxytocin, 1-butyric acid-2-(3-(p-methoxyphenyl)-L-alanine)oxytocinProducts: KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, KARPAVER 100 MCG/1 ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 5 ADET
  10. Drug

    Lumiracoxib

    go.drugbank.com/drugs/DB01283
    ApprovedWithdrawn

    Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID).

    Synonyms: 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acidCategories: COX-2 Inhibitors, Cytochrome P-450 Substrates