Decamethonium is used in anesthesia to cause paralysis. It is a short acting depolarizing muscle relaxant. It is similar to acetylcholine and acts as a partial agonist of the nicotinic...
- Mechanism
- Curator reviewed
Binds to the nicotinic acetycholine receptors (by virtue of its similarity to acetylcholine) in the motor endplate and blocks access to the receptors. In the process of binding, the receptor is actually activated - causing a process known as depolarization. Since it is not degraded in the neuromuscular junction, the depolarized membrance remains depolarized and unresponsive to any other impulse, causing muscle paralysis.
- Primary indication
- For use as a skeletal muscle relaxantCurator reviewed
- Formula / weight
- C16H38N2 · 258.4863 g/mol (avg)
- Also known as
- Decamethonium ion · Decamethonum
- Code names
- Lopac-D-1260
Resolves to
MTCUAOILFDZKCO-UHFFFAOYSA-NSMILESC[N+](C)(C)CCCCCCCCCC[N+](C)(C)CWhat you can answer from here — as of September 23, 2026
Which drugs share a target with Decamethonium, and which of those have an active Phase 3 trial?
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