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Displaying results 4451 - 4460 of 10000 in total
  1. Drug

    Sacubitril

    go.drugbank.com/drugs/DB09292
    ApprovedInvestigational

    It was approved by the FDA after being given the status of priority review for on July 7, 2015.

  2. Drug

    Sifalimumab

    go.drugbank.com/drugs/DB12773
    Investigational

    Sifalimumab may suppress the abnormal immune activity associated with lupus by binding to multiple interferon-alpha subtypes seen in the serum of lupus patients. … The levels of interferon-alpha are elevated in many patients with active systemic lupus erythematosus (SLE, or lupus) and other autoimmune disorders, and may be associated with disease activity.

  3. Target

    Nucleolar transcription factor 1

    go.drugbank.com/bio_entities/BE0012669
    TargetHumans

    Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I (Pol I) through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control ...

    Synonyms: Autoantigen NOR-90
  4. Drug

    Fasobegron

    go.drugbank.com/drugs/DB20200
    Experimental

    The usage of the INN stem '-begron' in the name indicates that Fasobegron is a β3​ adrenoreceptor agonists. Fasobegron has a monoisotopic molecular weight of 425.14 Da.

  5. Drug

    Ribuvaptan

    go.drugbank.com/drugs/DB20059
    Experimental

    The usage of the INN stem '-vaptan' in the name indicates that Ribuvaptan is a vasopressin receptor antagonist. Ribuvaptan has a monoisotopic molecular weight of 595.11 Da.

  6. Drug

    Filapixant

    go.drugbank.com/drugs/DB21467
    Experimental

    The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist. Filapixant has a monoisotopic molecular weight of 521.17 Da.

  7. Drug

    Teplinovivint

    go.drugbank.com/drugs/DB21475
    Experimental

    The usage of the INN stem '-vivint' in the name indicates that Teplinovivint is a Wnt signaling inhibitor. Teplinovivint has a monoisotopic molecular weight of 442.21 Da.

  8. Drug

    Ipivivint

    go.drugbank.com/drugs/DB21479
    Experimental

    The usage of the INN stem '-vivint' in the name indicates that Ipivivint is a Wnt signaling inhibitor. Ipivivint has a monoisotopic molecular weight of 464.19 Da.

  9. Drug

    Vornorexant

    go.drugbank.com/drugs/DB21483
    Experimental

    The usage of the INN stem '-orexant' in the name indicates that Vornorexant is a orexin receptor antagonist. Vornorexant has a monoisotopic molecular weight of 447.18 Da.

  10. Drug

    Enuvaptan

    go.drugbank.com/drugs/DB21492
    Experimental

    The usage of the INN stem '-vaptan' in the name indicates that Enuvaptan is a vasopressin receptor antagonist. Enuvaptan has a monoisotopic molecular weight of 576.09 Da.