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Biricodar
go.drugbank.com/drugs/DB04851InvestigationalThe pipecolinate derivative biricodar (VX-710) is a clinically applicable modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1).
Magnesium trisilicate
go.drugbank.com/drugs/DB09281ApprovedMagnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.
Felcisetrag
go.drugbank.com/drugs/DB12725InvestigationalFelcisetrag (TD-8954) has been used in trials studying the treatment of Enteral Feeding Intolerance and Gastrointestinal Motility Disorder.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAldosterone
go.drugbank.com/drugs/DB04630InvestigationalA hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
Lapyrium
go.drugbank.com/drugs/DB09376ApprovedLapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products . It is commonly found formulated as lapyrium chloride.
Ditazole
go.drugbank.com/drugs/DB08994ApprovedWithdrawnDitazole's analgesic and antipyretic effects are similar to phenylbutazone. Additionally, ditazole is a platelet aggregation inhibitor marketed in Spain and Portugal with trade name Ageroplas.
Indecainide
go.drugbank.com/drugs/DB00192ApprovedIndecainide has local anesthetic activity and belongs to the membrane stabilizing (Class 1) group of antiarrhythmic agents; it has electrophysiologic effects characteristic of the IC class of antiarrhythmics
Coronavirus-Like Particle COVID-19 Vaccine
go.drugbank.com/drugs/DB15852ExperimentalIn July 2020, Medicago partnered with Dynavax to test the vaccine with its adjuvant, Cpg 1018 (also known as [ISS-1018]), meant to provide an enhanced immune response to the vaccine. … The vaccine was developed by creating SARS-Cov-2 virus-like particles (CoVLPs), which mimic the structure of the virus without carrying the genetic components required for infection.
ADH-1
go.drugbank.com/drugs/DB05485InvestigationalPoorly differentiated, highly invasive carcinomas are characterized by over-expression of N-cadherin (as opposed to E-cadherin). … cadherin-mediated signaling, leading to apoptosis (death) of cancer cells