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Paltusotine
go.drugbank.com/drugs/DB16277ApprovedInvestigational[A269885, A274481] Paltusotine exhibits high affinity and selectivity towards SST2.[A274476] Paltusotine was approved by the FDA on September 25, 2025 for the treatment of acromegaly in adults. … selective somatostatin receptor agonist: It mimics the biological actions of endogenous somatostatin, which activates the somatostatin 2 receptor (SST2) to block the secretion of growth hormone (GH) and
Imidafenacin
go.drugbank.com/drugs/DB09262InvestigationalIt is marketed in Japan under the tradenames Staybla by Ono Pharmaceutical and Uritos by Kyojin Pharmaceutical. … Imidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder.
Categories: Genito Urinary System and Sex Hormones, Drugs for Urinary Frequency and IncontinenceCorticorelin
go.drugbank.com/drugs/DB05394InvestigationalIt is made naturally by the hypothalamus (a part of the brain) and can also be made in the laboratory. … Human corticotropin-releasing factor may help reduce symptoms caused by edema (swelling) of the brain. It is a type of neurohormone, also called hCRF.
Categories: Amino Acids, Peptides, and Proteins, Hormones, Hormone Substitutes, and Hormone AntagonistsProducts: CRH "Ferring" - Pulver und Lösungsmittel zur Herstellung einer InjektionslösungMuparfostat
go.drugbank.com/drugs/DB05808InvestigationalMuparfostat (PI-88) is a mixture of highly sulfated, monophosphorylated mannose oligosaccharides, derived from the extracellular phosphomannan of the yeast Pichia (Hansenula) holstii, with potential antiangiogenic
Carbenicillin
go.drugbank.com/drugs/DB00578ApprovedIt is susceptible to gastric juice and penicillinase and may damage platelet function.
Gadopiclenol
go.drugbank.com/drugs/DB17084ApprovedInvestigational[L43817] In 2006, the use of GBCAs was associated with the development of nephrogenic systemic fibrosis (NSF), a rare disorder characterized by the thickening and hardening of skin and subcutaneous tissues … It is indicated for use with magnetic resonance imaging (MRI) to detect and visualize lesions with abnormal vascularity in the central nervous system and the body.
Pegulicianine
go.drugbank.com/drugs/DB18731ApprovedInvestigational[L50537] Pegulicianine (under the brand name Lumisight) was approved for use by the FDA in April 2024.[L50537,L50547] It received Fast Track and priority review for this indication.[L50547] … Pegulicianine is an optical imaging agent indicated for fluorescence imaging in patients with breast cancer.
Categories: Indicators and Reagents, Amino Acids, Peptides, and ProteinsEribulin
go.drugbank.com/drugs/DB08871ApprovedInvestigationalEribulin was isolated from the marine sponge Halichondria okadai. Eribulin is also being investigated for use in the treatment of advanced solid tumors [A7439].
Categories: Antineoplastic and Immunomodulating AgentsHalcinonide
go.drugbank.com/drugs/DB06786ApprovedWithdrawnHalcinonide is a corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, and is distributed as a cream and ointment. … Halcinonide is marketed under the brand name Halog® by Ranbaxy Laboratories Inc.
Haemophilus influenzae type B capsular polysaccharide meningococcal outer membrane protein conjugate antigen
go.drugbank.com/drugs/DB10342ApprovedInvestigationalHaemophilus influenzae type b capsular polysaccharide meningococcal outer membrane protein conjugate antigen is a vaccine containing outer membrane antigen extracted from *Haemophilus influenzae*.