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Teriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalTeriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. … It is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersSynonyms: (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidideCodeine
go.drugbank.com/drugs/DB00318ApprovedIllicitInvestigationalCodeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or altering other sensory … [A175096] Codeine is utilized as a central analgesic, sedative, hypnotic, antinociceptive, and antiperistaltic agent, and is also recommended in certain diseases with incessant coughing.
Synonyms: L-Codeine, (5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-olMixtures: A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 20 ADET, A-FERİN 300 MG/2 MG/10 MG KAPSÜL, 500 ADETFludeoxyglucose (18F)
go.drugbank.com/drugs/DB09502ApprovedInvestigationalFludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with
Synonyms: Fluorine-18 2-Fluoro-2-deoxy-D-Glucose, 18-F FDGCategories: Compounds used in a research, industrial, or household settingNADH-ubiquinone oxidoreductase chain 4
go.drugbank.com/bio_entities/BE0000551TargetHumansCore subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:15250827, PubMed:8344...
Polypeptides: NADH-ubiquinone oxidoreductase chain 4Synonyms: NADH dehydrogenase subunit 4tRNA wybutosine-synthesizing protein 4
go.drugbank.com/bio_entities/BE0000613TargetHumansWybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (Probable) … S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway (Probable).
Polypeptides: tRNA wybutosine-synthesizing protein 4Synonyms: tRNA yW-synthesizing protein 4Glutathione S-transferase Mu 4
go.drugbank.com/bio_entities/BE0000812TargetHumansCan also catalyze the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator … Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed:8203914, PubMed:8373352).
Polypeptides: Glutathione S-transferase Mu 4Synonyms: GSTM4-4, GST class-mu 4Protein-glutamine gamma-glutamyltransferase 4
go.drugbank.com/bio_entities/BE0002243EnzymeTargetHumansAssociated with the mammalian reproductive process. Catalyzes the cross-linking of proteins and the conjugation of polyamines to specific proteins in the seminal tract
Polypeptides: Protein-glutamine gamma-glutamyltransferase 4Synonyms: TGase-4, Transglutaminase-4Neuropeptide Y receptor type 4
go.drugbank.com/bio_entities/BE0002418TargetHumansG protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP (PubMed:7493937, PubMed:7592911). The rank order of affinity for these polypeptides and their derivati...
Polypeptides: Neuropeptide Y receptor type 4Proteasome subunit alpha type-4
go.drugbank.com/bio_entities/BE0003913TargetHumansThis type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex) … The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are
Polypeptides: Proteasome subunit alpha type-4Hepatocyte nuclear factor 4-alpha
go.drugbank.com/bio_entities/BE0004019TargetHumansTranscriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922)...
Polypeptides: Hepatocyte nuclear factor 4-alphaSynonyms: Nuclear receptor subfamily 2 group A member 1, HNF-4-alpha