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Displaying results 441 - 450 of 10000 in total
  1. Drug

    Azacitidine

    go.drugbank.com/drugs/DB00928
    ApprovedInvestigational

    [A1415] The use of oral azacitidine for the treatment of AML in patients in complete remission was approved by the FDA in September 2020.[L35335] … It differs from cytosine by the presence of nitrogen in the C5-position, key in its hypomethylating activity.[A1406,A1413,A1415] Two main mechanisms of action have been proposed for azacitidine.

    Products: AZACITIDINA EG
  2. Drug

    Minoxidil

    go.drugbank.com/drugs/DB00350
    ApprovedInvestigational

    A potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.

    Categories: Arteriolar Smooth Muscle, Agents Acting OnProducts: TRIATOP®ESPUMA TÓPICA EN AEROSOL, TYLCORE® ESPUMA TÓPICA EN AEROSOL
  3. Drug

    Folic acid

    go.drugbank.com/drugs/DB00158
    ApprovedInvestigationalNutraceuticalVet approved

    [L5744] In order to function within the body, folic acid must first be reduced by the enzyme dihydrofolate reductase (DHFR) into the cofactors dihydrofolate (DHF) and tetrahydrofolate (THF). … Folic acid, also known as folate or Vitamin B9, is a member of the B vitamin family and an essential cofactor for enzymes involved in DNA and RNA synthesis.

    Mixtures: Supravite Stress Avec Vit E Et Fer, SetonET-ECSynonyms: N-pteroyl-L-glutamic acid, N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
  4. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Losartan was granted FDA approval on 14 April 1995.[L7423] … Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension.

    Mixtures: LOSARTAN E IDROCLOROTIAZIDE EG, LOSARTAN E IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin System
  5. Drug

    Perindopril

    go.drugbank.com/drugs/DB00790
    ApprovedInvestigational

    It is rapidly metabolized in the liver to perindoprilat, its active metabolite, following oral administration.

    Mixtures: PERINDOPRIL E AMLODIPINA EG, PERINDOPRIL E AMLODIPINA EGCategories: Agents Acting on the Renin-Angiotensin System
  6. Drug

    Docusate

    go.drugbank.com/drugs/DB11089
    Approved

    Still docusate is available in over-the-counter products as a common laxative. … Docusate is on the World Health Organization's List of Essential Medicines[L5915].

    Mixtures: E-Vac Plus, EX-lax Gentle StrengthProducts: H E B Stool Softener laxative, EX-lax Stool Softener - Tab 100 mg
  7. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    regulation in both children and adults. … [A228183] Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and lipid

    Products: OMNITROPE® SOLUCION INYECTABLE EN CARTUCHO DE 10 MG / 1.5 ML, Nutropin AQ Pen 10
  8. Target

    Protein S100-A12

    go.drugbank.com/bio_entities/BE0001206
    TargetHumans

    S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its pro-inflammatory activity involves recruitment of leukocytes, promotion of cytokine...

    Synonyms: EN-RAGE
  9. Drug

    Bicalutamide

    go.drugbank.com/drugs/DB01128
    ApprovedInvestigational

    Bicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers.

    Products: BICALUTAMIDE EG, BICALUTAMIDE EG STADA
  10. Drug

    Mineral oil

    go.drugbank.com/drugs/DB11057
    ApprovedInvestigationalVet approved

    Mineral oil is a common ingredient in baby lotions, cold creams, ointments and cosmetics to treat and prevent dry, rough, scaly, itchy skin and minor skin irritations.

    Products: Truffle EX Cleansing