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Nimodipine
go.drugbank.com/drugs/DB00393ApprovedInvestigationalCompared to other calcium channel blocking agents, nimodipine exhibits greater effects on cerebral circulation than on peripheral circulation. … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Products: NIMODIPINA EGRanolazine
go.drugbank.com/drugs/DB00243ApprovedInvestigationalIt was originally approved by the FDA in 2006.[L5440]
Products: RANOLAZINA EGAmisulpride
go.drugbank.com/drugs/DB06288ApprovedInvestigational[A6752, L32764] Oral tablets of amisulpride is used in European countries as a treatment for acute and chronic schizophrenic disorders, as well as secondary negative symptoms in mental health disorders … [A6755] Amisulpride predominantly works in the limbic system, which explains its relatively lower risk of extrapyramidal adverse effects compared to other atypical antipsychotic agents.
Synonyms: 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-O-anisamide, 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamideProducts: AMISULPRIDE EGPyruvate Dehydrogenase Complex Deficiency
smpdb.ca/view/SMP0125772DiseasePDHA1 encodes the pyruvate dehydrogenase complex (PDC) a critical complex that converts pyruvate from glycolysis to acetyl CoA for the citric acid cycle. … Pyruvate dehydrogenase complex deficiency results from a mutation in the E1-alpha polypeptide gene (PDHA1).
Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialPrednisone
go.drugbank.com/drugs/DB00635ApprovedInvestigationalVet approved[A187463] It is biologically inert and converted to [prednisolone] in the liver.[L10502] Prednisone was granted FDA approval on 21 February 1955.[L10496]
Products: PREDNISONE EGRisedronic acid
go.drugbank.com/drugs/DB00884ApprovedInvestigationalRisedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label] . It functions by preventing resorption of bone[FDA Label] .
Products: RISEDRONATO EG, RISEDRONATO EG STADATeriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalTeriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. … The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.
Products: TERIFLUNOMIDE EGGliclazide
go.drugbank.com/drugs/DB01120ApprovedInvestigationalMedications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. … [A39546] On the other hand, based on the pharmacological efficacy, gliclazide is considered a second-generation sulfonylurea which presents a higher potency and a shorter half-life.
Categories: Drugs Used in DiabetesProducts: GLICLAZIDE EG, GLICLAZIDE EG STADADutasteride
go.drugbank.com/drugs/DB01126ApprovedInvestigationalDutasteride was approved by the FDA in 2001 for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men as monotherapy or in combination with the α-adrenergic antagonist [tamsulosin] to … trials in androgenetic alopecia.
Mixtures: Aglandin comp. 0,5 mg/0,4 mg-Hartkapseln, DUTASTERIDE E TAMSULOSINA DOCCategories: Drugs Used in Benign Prostatic HypertrophyGanciclovir
go.drugbank.com/drugs/DB01004ApprovedInvestigationalAn acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
Products: Ganciclovir Oresund Pharma 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung