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Displaying results 4491 - 4500 of 10000 in total
  1. Drug

    Nalorphine

    go.drugbank.com/drugs/DB11490
    ExperimentalVet approved

    It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence. … Nalorphine is a mixed opioid agonist–antagonist.

    Categories: Heterocyclic Compounds with 4 or More Rings
  2. Drug

    Human calcitonin

    go.drugbank.com/drugs/DB06773
    Approved

    [A32099] It is constituted as a 32-amino acid single chain polypeptide structure that gets secreted as a regulatory agent in calcium-phosphorus metabolism. … Calcitonin was first discovered in isolated parathyroid tissue as a substance with a serum-calcium-lowering effect.

  3. Drug

    Calcipotriol

    go.drugbank.com/drugs/DB02300
    ApprovedInvestigational

    Calcipotriol (INN) or calcipotriene (USAN) is a sythetic derivative of calcitriol or Vitamin D.

    Mixtures: Daivobet Gel 50mcg/g + 0.5mg/g, DAIVOBET® GEL 50 MCG + 0.5 MG/ GCategories: Vitamin D and Analogues
  4. Drug

    Tagatose

    go.drugbank.com/drugs/DB04936
    Investigational

    It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only a third of the calories. It is approved as a food additive as a low calorie sweetener. … Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes.

    Synonyms: (3S,4S,5R)-1,3,4,5,6-pentahydroxyhexan-2-one, D-lyxo-hex-2-uloseCategories: Compounds used in a research, industrial, or household setting
  5. Drug

    CZEN 002

    go.drugbank.com/drugs/DB05479
    Experimental

    (6-9) that is important for binding to the known melanocortin receptors. … A second focus was on the sequence Lys-Pro-Val (11-13) that is known to be important for antimicrobial activity.

  6. Drug

    LC16M8

    go.drugbank.com/drugs/DB05019
    Investigational

    LC16m8 is a next-generation, attenuated smallpox vaccine that is designed to have a better safety profile, yet be equally effective, compared to conventional smallpox vaccines. … It is the only attenuated vaccine to be licensed for use in humans to prevent smallpox infection.

  7. Drug

    Mercaptopurine

    go.drugbank.com/drugs/DB01033
    ApprovedInvestigational

    It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.

    Synonyms: 6 MP, 6-MPCategories: Heterocyclic Compounds, 2-Ring, OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index
  8. Drug

    Chloride ion

    go.drugbank.com/drugs/DB14547
    Investigational

    Synonyms: Chloride(1-)Mixtures: SH NEOLPHAR, Telom-X-gene
  9. Drug

    Sitimagene ceradenovec

    go.drugbank.com/drugs/DB04907
    Experimental

    Sitimagene ceradenovec is a novel gene-based product for the treatment of patients with operable high grade glioma, a type of malignant brain tumour, given in addition to standard surgery and radiotherapy … It is being developed by Ark Therapeutics.

  10. Drug

    Cintredekin besudotox

    go.drugbank.com/drugs/DB05305
    Investigational

    Cintredekin besudotox is made from a human protein, Interleukin 13 (IL13), linked to a bacterial toxin, _Pseudomonas exotoxin_ (PE). The IL13 portion binds to receptors on the tumor. … Cintredekin besudotox has been developed as a specific tumor-targeting agent, which is administered by positive-pressure convection-enhanced delivery (CED) directly to brain tissue at risk for residual