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Displaying results 4491 - 4500 of 10000 in total

Indication
Tenia Solium Infection
go.drugbank.com/conditions/DBCOND0056943
Drugs: Mebendazole
Synonyms: Taenia solium infection, intestinal form, Taenia solium infection, intestinal form (disorder) [Ambiguous]
Drug
CM4620
go.drugbank.com/drugs/DB16466
Investigational
CM4620 (Zegocractin), is under investigation in multiple clinical trials, including NCT04195347 (pancreatitis due to asparaginase), NCT03709342 (PK/PD study in acute pancreatitis), NCT03401190 and NCT04681066
Synonyms: BENZAMIDE, N-(5-(6-CHLORO-2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-2-PYRAZINYL)-2-FLUORO-6-METHYL-, N-(5-(6-CHLORO-2,2-DIFLUOROBENZO(D)(1,3)DIOXOL-5-YL)PYRAZIN-2-YL)-2-FLUORO-6-METHYLBENZAMIDECategories: Experimental Unapproved Treatments for COVID-19
Drug
Theobromine
go.drugbank.com/drugs/DB01412
Investigational
It has a weaker diuretic activity than theophylline and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. … Theobromine (3,7-dimethylxanthine) is the principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator.
Categories: Drugs for Obstructive Airway Diseases
Drug
Danazol
go.drugbank.com/drugs/DB01406
ApprovedInvestigational
It possesses some androgenic properties. Danazol has been used in the treatment of endometriosis and some benign breast disorders. … A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins.
Drug
Linrodostat
go.drugbank.com/drugs/DB14986
Investigational
Linrodostat is under investigation in clinical trial NCT03247283 (Pharmacokinetics and Metabolism Study in Healthy Male Participants).
Drug
Thioridazine
go.drugbank.com/drugs/DB00679
ApprovedWithdrawn
A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. … Thioridazine was withdrawn worldwide in 2005 due to its association with cardiac arrythmias.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine
Drug
Progabide
go.drugbank.com/drugs/DB00837
Experimental
In clinical trials, progabide has been investigated for Parkinson's disease, schizophrenia, clinical depression and anxiety disorder; its therapeutic effectiveness in these conditions is not fully elucidated … Progabide is an analog and prodrug of gamma-aminobutyric acid. It is commonly used in the treatment of epilepsy. It has agonistic activity for both the GABAA and GABAB receptors.
Drug
Motexafin gadolinium
go.drugbank.com/drugs/DB05428
Investigational
Motexafin gadolinium is studied in the treatment of cancer by Pharmacyclics. … It belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds with 4 or More Rings
Drug
PF-06260414
go.drugbank.com/drugs/DB15221
Investigational
PF-06260414 is under investigation in clinical trial NCT02070939 (Study To Evaluate Safety And Tolerability Of Single And Multiple Ascending Doses Of PF- 06260414 In Healthy Western And Japanese Male Subjects
Drug
DFV890
go.drugbank.com/drugs/DB16461
Investigational
DFV890 is under investigation in multiple clinical trials for its efficacy, safety, and tolerability across various conditions: NCT06031844 (coronary heart disease with elevated hsCRP), NCT04886258 (symptomatic
Categories: Experimental Unapproved Treatments for COVID-19