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Dorzagliatin
go.drugbank.com/drugs/DB15123InvestigationalDorzagliatin is under investigation in clinical trial NCT03173391 (Long-term Efficacy and Safety of HMS5552 in T2DM).
Categories: Drugs Used in DiabetesEdaxeterkib
go.drugbank.com/drugs/DB21490InvestigationalEdaxeterkib is under investigation in clinical trial NCT03051035 (First-in-Human Study of KO-947 in Non-Hematological Malignancies). Edaxeterkib has a monoisotopic molecular weight of 469.22 Da. … The usage of the INN stem '-terkib' in the name indicates that Edaxeterkib is a extracellular signal-regulated kinase (ERK) inhibitor.
Sulfabenzamide
go.drugbank.com/drugs/DB09355ApprovedWithdrawnSulfabenzamide is an antimicrobial agent often used in conjunction with sulfathiazole and sulfacetamide as a topical intravaginal antibacterial preparation.
Synonyms: N-Benzoylsulfanilamide, N-SulfanilylbenzamideAlverine
go.drugbank.com/drugs/DB01616ApprovedInvestigationalWithdrawnIt is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions. It can also be used to help relieve period pain.
Synonyms: Di(phenylpropyl)ethylamine, N,N-Bis(3-phenylpropyl)ethylamineTrinitrotoluene
go.drugbank.com/drugs/DB01676ExperimentalTrinitrotoluene is an explosive chemical that can cause skin irritation and other toxic consequences.
Categories: Compounds used in a research, industrial, or household settingPrimaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigational(From Martindale, The Extra Pharmacopeia, 30th ed, p404) … An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide.
Anethole
go.drugbank.com/drugs/DB15916ApprovedWithdrawnSynonyms: (E)-AnetholeCategories: Compounds used in a research, industrial, or household settingATN-161
go.drugbank.com/drugs/DB05491InvestigationalIt inhibits the migration and adhesion of particular integrins on activated endothelial cells that play a critical role in tumor angiogenesis. … This approach targeting both the tumor vasculature and the cancer cells themselves, may be effective in single therapy as well as combination therapy.
PAC-113
go.drugbank.com/drugs/DB05756InvestigationalPAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva. … PAC-113 is targeting oral Candida infections in immunocompromised patients and patients with salivary dysfunction.
DS-1211
go.drugbank.com/drugs/DB17837InvestigationalDS-1211 is a potent and selective novel small molecule tissue-nonspecific alkaline phosphatase (TNAP) inhibitor.[A259786]
Synonyms: N-Acetyl-D-leucine, D-leucine, N-acetyl-