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Displaying results 4501 - 4510 of 10000 in total
  1. Drug

    Zinc acetate

    go.drugbank.com/drugs/DB14487
    ApprovedInvestigational

    Mixtures: Diphenhydramine D, CALPRAX CLEAR®Products: Senior B, Neat 3B Baby B
  2. Drug

    Ustekinumab

    go.drugbank.com/drugs/DB05679
    ApprovedInvestigational

    Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses. … [A187346] The therapeutic use of the drug started in Canada, the US, and Europe since 2009 when it was first approved for the treatment of adult patients with moderate to severe plaque psoriasis and

    Categories: Skin and Mucous Membrane AgentsProducts: STELARA® 45 MG/0.5 ML, Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mL
  3. Target

    ADP-L-glycero-D-manno-heptose-6-epimerase

    go.drugbank.com/bio_entities/BE0001296
    TargetEscherichia coli (strain K12)

    Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.

    Polypeptides: ADP-L-glycero-D-manno-heptose-6-epimeraseSynonyms: ADP-hep 6-epimerase, ADP-glyceromanno-heptose 6-epimerase
  4. Target

    Potassium voltage-gated channel subfamily A member 6

    go.drugbank.com/bio_entities/BE0004718
    TargetHumans

    Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient (Pu...

    Polypeptides: Potassium voltage-gated channel subfamily A member 6
  5. Drug

    Ethanol

    go.drugbank.com/drugs/DB00898
    ApprovedInvestigational

    It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. … A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant.

    Mixtures: Adventure Medical Kits 1-4 Person First Aid, Refill 6Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 Substrates
  6. Drug

    Ranitidine

    go.drugbank.com/drugs/DB00863
    ApprovedWithdrawn

    Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine]. … [L10818,F4253] The prevalence of GERD is thought to be 10-20% in western countries.

    Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: RANITIDINA SUN, RECEFAR® 300 MG TABLETAS CUBIERTAS
  7. Drug

    Cholecalciferol

    go.drugbank.com/drugs/DB00169
    ApprovedInvestigationalNutraceutical

    Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689]. … Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation

    Synonyms: Vitamin D 3, Vitamin D-3International brands: Delta-D, Micro-D
  8. Drug

    Rabeprazole

    go.drugbank.com/drugs/DB01129
    ApprovedInvestigational

    Rabeprazole is an antiulcer drug in the class of proton pump inhibitors. It is a prodrug - in the acid environment of the parietal cells it turns into active sulphenamide form. … Rabeprazole inhibits the H+, K+ATPase of the coating gastric cells and dose-dependent oppresses basal and stimulated gastric acid secretion.

    Mixtures: RASOFORCE 20/1680 MG TOZ İÇEREN SAŞE, 14 SAŞE, RABEDIC 10/75 MG MR KAPSÜL, 20 ADETCategories: Cytochrome P-450 Substrates, 2-Pyridinylmethylsulfinylbenzimidazoles
  9. Drug

    Meloxicam

    go.drugbank.com/drugs/DB00814
    ApprovedInvestigationalVet approved

    [A190189] With a longer half-life than most other NSAIDS, it is a favorable option for those who require once-daily dosing. Meloxicam is available in oral, transdermal, and intravenous formulations. … It is a preferential COX-2 inhibitor, purportedly reducing the risk of adverse gastrointestinal tract effects, however, this is a topic of controversy.[A190198,A190201]

    Mixtures: OCAM PROTECT ® 15 MG TABLETAS DE LIBERACION RETARDADA, NuDroxiPAK M-15Categories: COX-2 Inhibitors, Cytochrome P-450 Substrates
  10. Drug

    Fluticasone propionate

    go.drugbank.com/drugs/DB00588
    ApprovedInvestigational

    Fluticasone propionate is a synthetic glucocorticoid[F4355,F4358][FDA Label]. … Fluticasone propionate was first approved in 1990[L5962].

    Mixtures: Fluticasone Propionate 0.05% / Niacinamide 4%, SUN RHEORAN SF INHALER 25/125 mcgCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates