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Displaying results 4531 - 4540 of 7897 in total
  1. Drug

    N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide

    go.drugbank.com/drugs/DB06944
    Experimental

    These are compounds containing a naphthalene moiety, which consists of two fused benzene rings. … N-(3-cyclopropyl-1H-pyrazol-5-yl)-2-(2-naphthyl)acetamide is a solid. This compound belongs to the naphthalenes.

  2. Drug

    α-Methylacetylfentanyl

    go.drugbank.com/drugs/DB01532
    ExperimentalIllicit

    α-Methylacetylfentanyl is an analog of fentanyl with opioid analgesic properties.

  3. Drug

    R411

    go.drugbank.com/drugs/DB05468
    Experimental

    It is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7. … R411 is a non-steroid oral medicine for the treatment of asthma. It is not immunosuppressive, but blocks the activation and recruitment of cells involved in respiratory inflammation.

  4. Drug

    5-Methoxy-N,N-diisopropyltryptamine

    go.drugbank.com/drugs/DB01441
    ExperimentalIllicit

    5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine, … Since 1999, there has been a growing popularity of 5-MeO-DIPT among drug abusers. This substance is abused for its hallucinogenic effects.

  5. Drug

    Guanosine tetraphosphate

    go.drugbank.com/drugs/DB04022
    Experimental

    This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. … Guanosine tetraphosphate is a guanine nucleotide containing four phosphate groups.

  6. Drug

    Tozasertib

    go.drugbank.com/drugs/DB19675
    Investigational

    Tozasertib is a small molecule drug. The usage of the INN stem '-sertib' in the name indicates that Tozasertib is a serine/threonine kinase inhibitor. … Tozasertib has a monoisotopic molecular weight of 464.21 Da.

  7. Drug

    Antilymphocyte immunoglobulin (horse)

    go.drugbank.com/drugs/DB09312
    ApprovedInvestigational

    It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen. … The result is polyclonal IgG that is then purified from the horse's serum to produce a usable drug product that can be used for immunosuppression.

  8. Drug

    Kinetin

    go.drugbank.com/drugs/DB11336
    Approved

    While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents. … Kinetin is a cytokinin which are plant hormones promotes cell division and plant growth. It was shown to naturally exist in DNA of organisms including humans and various plants.

  9. Drug

    Reboxetine

    go.drugbank.com/drugs/DB00234
    ApprovedInvestigationalWithdrawn

    Reboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD. … Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.

  10. Drug

    Infigratinib

    go.drugbank.com/drugs/DB11886
    ApprovedInvestigationalWithdrawn

    [A198963] Infitratinib is a pan-FGFR inhibitor, as it is an ATP-competitive inhibitor of all four FGFR receptor subtypes. … fibroblast growth factor receptor 2 (FGFR2) fusion or another rearrangement as detected by an FDA-approved test.