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Dapansutrile
go.drugbank.com/drugs/DB16130InvestigationalDapansutrile is under investigation in clinical trial NCT01768975 (Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee).
Desidustat
go.drugbank.com/drugs/DB16135InvestigationalDesidustat is under investigation in clinical trial NCT04012957 (Desidustat in the Treatment of Anemia in CKD).
Moroctocog alfa
go.drugbank.com/drugs/DB13999ApprovedAs it does not contain von Willebrand factor it is not indicated in von Willebrand’s disease [L41170]. … Also known as Anti-Hemophilic Factor (AHF), endogenous Factor VIII is essential to the clotting process in the body due to its involvement in the clotting cascade where it is responsible for acting as
XPro1595
go.drugbank.com/drugs/DB16454InvestigationalXPro1595 is an investigational dominant-negative protein that neutralizes soluble TNF.
Anacaulase
go.drugbank.com/drugs/DB17449ApprovedInvestigationalIt is mostly composed (80-95% w/w) of proteins such as stem bromelain, ananain, jacalin-like lectin, bromelain inhibitors, and phytocystatin inhibitor, as well as saccharides, as both free monosaccharides
Sulindac
go.drugbank.com/drugs/DB00605ApprovedInvestigationalLike other NSAIDs, it may be used in the treatment of acute or chronic inflammatory conditions.
Products: CLINORIL 200 MG TABLETASLevamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer.
Products: PARAKS 40 MG TABLET, 6 ADET, PARAKS 40 MG/5 ML ŞURUP, 30 MLTolbutamide
go.drugbank.com/drugs/DB01124ApprovedIt is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin
Products: TOLMIDE TABLET 500 mg, TOBUMIDE TABLET 500 mgAC3056
go.drugbank.com/drugs/DB05230ExperimentalIt as since been acquired by Amylin Pharmaceuticals and has completed phase I trials.
P54
go.drugbank.com/drugs/DB05451ExperimentalIt inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and iNOS.