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Displaying results 4551 - 4560 of 10000 in total
  1. Drug

    Rhein

    go.drugbank.com/drugs/DB13174
    Experimental

    Rhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis [A19247]

  2. Drug

    Tropisetron

    go.drugbank.com/drugs/DB11699
    ApprovedInvestigationalWithdrawn

    As a selective serotonin receptor antagonist, tropisetron competitively blocks the action of serotonin at 5HT3 receptors, resulting in suppression of chemotherapy- and radiotherapy-induced nausea and vomiting … Tropisetron is an indole derivative with antiemetic activity.

  3. Drug

    MKC1106-PP

    go.drugbank.com/drugs/DB06030
    Experimental

    MKC1106-PP is a 3-component investigational vaccine made up of a DNA plasmid (pPRA-PSM) and 2 peptides E-PRA and E-PSM. … MKC1106-PP was under investigation in clinical trial NCT00423254 (Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.).

  4. Drug

    AZX-100

    go.drugbank.com/drugs/DB06323
    Investigational

  5. Drug

    Cixutumumab

    go.drugbank.com/drugs/DB12250
    Investigational

    Cixutumumab is a highly specific recombinant human monoclonal antibody with high affinity for the insulin-like growth factor-I receptor (IGF-IR). IGF-IR is overexpressed in a variety of tumour types. … Cixutumumab has been used in trials studying the treatment of Lung Cancer, Malignant Neoplasm, Leukemia, Mast-Cell, Non-Small-Cell Lung Carcinoma, and Adenocarcinoma of the Prostate.

  6. Drug

    Zanapezil

    go.drugbank.com/drugs/DB04859
    Experimental

    Zanapezil (TAK-147) is a selective acetylcholine (ACh) esterase inhibitor under investigation as a drug for Alzheimer's disease (AD) treatment.

  7. Drug

    Flurazepam

    go.drugbank.com/drugs/DB00690
    ApprovedIllicit

    A benzodiazepine derivative used mainly as a hypnotic.

  8. Drug

    Abdavomeran

    go.drugbank.com/drugs/DB15695
    Investigational

    [L15012] The modRNA is formulated in lipid nanoparticles for delivery via intramuscular injection. … -19 convalescent plasma] 28 days after initial immunization of either 10 or 30μg of BNT162b1, with further improvements following a second dose.

    Categories: Experimental Unapproved Treatments for COVID-19
  9. Drug

    ATX-101

    go.drugbank.com/drugs/DB05780
    Investigational

    ATX-101 demonstrates a relative selectivity for fat over other tissues. … ATX-101 (medical), sodium deoxycholate for subcutaneous injection, is being evaluated as a treatment for the reduction of localized fat deposits.

  10. Drug

    Plozalizumab

    go.drugbank.com/drugs/DB12520
    Investigational

    Plozalizumab has been investigated for the treatment of Atherosclerosis. … The recruitment of macrophages to the arterial wall is believed to be a critical step in the development of atherosclerosis.