Search

Displaying results 4581 - 4590 of 10000 in total
  1. Drug

    Ad5-nCoV

    go.drugbank.com/drugs/DB15655
    Investigational

    The study will evaluate antibody response in healthy patients between the ages of 18 and 60 who will receive one of three study doses, with follow-up taking place at weeks 2 and 4 and months 3 and 6 post-vaccination … )[L12675] with an expected completion in December 2020.

  2. Drug

    Acrivastine

    go.drugbank.com/drugs/DB09488
    Approved

    , edema, bronchoconstriction, and tachycardia. … As an H1 receptor antagonist, it functions by blocking the action of histamine at this receptor thereby preventing the symptoms associated with histamine release such as pruritis, vasodilation, hypotension

  3. Drug

    Vorinostat

    go.drugbank.com/drugs/DB02546
    ApprovedInvestigational

    Vorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease persists, gets worse, or comes...

    Categories: Antineoplastic and Immunomodulating Agents
  4. Drug

    Fludrocortisone

    go.drugbank.com/drugs/DB00687
    ApprovedInvestigational

    [A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position

    Categories: Sex Hormones and Insulins, fludrocortisone and antiinfectives
  5. Drug

    Benfluorex

    go.drugbank.com/drugs/DB09022
    ApprovedWithdrawn

    Benfluorex is an anorectic and hypolipidemic agent that is structurally related to fenfluramine. It was patented and manufactured by a French pharmaceutical company Servier.

    Categories: Alimentary Tract and Metabolism
  6. Drug

    Olaratumab

    go.drugbank.com/drugs/DB06043
    ApprovedInvestigational

    It is composed of two heavy chain molecule fragments and 2 light chain fragments. … Studies show that the treatment of olaratumab in combination with doxorubicin resulted in significant reduction of cancer cell proliferation and tumor growth.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents
  7. Drug

    Tavaborole

    go.drugbank.com/drugs/DB09041
    Approved

    Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu). … Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes

  8. Indication

    Systemic Mastocytosis With an Associated Hematological Neoplasm

    go.drugbank.com/conditions/DBCOND0135968
    Drugs: Avapritinib
    Synonyms: Systemic Mastocytosis With an Associated Hematologic Neoplasm, Systemic Mastocytosis With an Associated Hematological Neoplasm
  9. Drug

    Isopropyl myristate

    go.drugbank.com/drugs/DB13966
    Approved

    Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. … Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.

    Categories: Scabicides and Pediculicides
  10. Drug

    Elacestrant

    go.drugbank.com/drugs/DB06374
    ApprovedInvestigational

    Elacestrant is a non-steroidal small molecule and an estrogen receptor (ER) antagonist. … [L49334] Elacestrant binds to estrogen receptor-alpha (ERα) and acts as a selective estrogen receptor degrader (SERD) thanks to its ability to block the transcriptional activity of the ER and promote

    Categories: Antineoplastic and Immunomodulating Agents, Hormone Antagonists and Related Agents