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Chlorine dioxide
go.drugbank.com/drugs/DB12453ApprovedChlorine Dioxide has been used in trials studying the treatment of Halitosis.
Categories: Compounds used in a research, industrial, or household settingProducts: Skin N Clean, Pure O2-S FIodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalFor this reason, less toxic iodine isotopes such as I-123 are more frequently used in nuclear imaging, while I-131 is reserved for its tissue destroying effects. … Iodide I-131 (as Sodium iodide I-131) is a radioisotopic drug used for the treatment and palliation of thyroid malignancy.
Salts: Sodium iodide I-131Synonyms: 131 I, 131-ISetmelanotide
go.drugbank.com/drugs/DB11700ApprovedInvestigational[A224449] Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. … [L24474] It is an agonist of the melanocortin 4 receptor.
Categories: Melanocortin 4 Receptor Agonist, Melanocortin 4 Receptor AgonistsBenserazide
go.drugbank.com/drugs/DB12783ApprovedInvestigationalWhen levodopa is used by itself as a therapy for treating Parkinson's disease, its ubiquitous metabolism into dopamine is responsible for a resultant increase in the levels of circulating dopamine in the … combination in the form of levodopa and carbidopa.
Mixtures: MADOPAR®, MADOPAR®Categories: Aromatic L-amino Acid Decarboxylase InhibitorsPhloxine B
go.drugbank.com/drugs/DB13911ApprovedWithdrawnPhloxine B (commonly known simply as phloxine, also known as D&C RED NO. 28) is a color additive which is used both as an inactive ingredient to provide color to products, or as a colorant in dental disclosing … These tablets allow patients to visualise areas where more brushing and flossing are needed.
Categories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitorsSynonyms: D&C Red No. 28, CI Acid Red 92Trospium
go.drugbank.com/drugs/DB00209ApprovedInvestigational[L6208] Trospium is manufactured by _Indevus Pharmaceutical Inc._ and was granted FDA approval in 2007.[L6211] … Trospium is an antispasmodic agent used to treat the symptoms of overactive bladder, a condition that causes the bladder muscles to contract uncontrollably.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsInternational brands: Tropez ODPerfluorohexyloctane
go.drugbank.com/drugs/DB17823ApprovedInvestigational[A259746] Because it is a completely non-aqueous liquid, microbial growth is not possible; therefore, its drug products do not need to be combined with any preservative. … [A259746, A259751] Perfluorohexyloctane has been used in the field of ophthalmology as a vitreous substitute.
Synonyms: 1-(perfluorohexyl)octaneInebilizumab
go.drugbank.com/drugs/DB12530ApprovedInvestigational[L14315] Given its mechanism of action and good safety profile, it may prove useful in the treatment of other conditions linked to autoimmune antibody production or B-cell malignancies. … Inebilizumab is cytolytic, resulting in B-cell depletion and offering therapeutic benefit to patients suffering from NMOSD.
Products: UPLIZNA®Acoramidis
go.drugbank.com/drugs/DB17999ApprovedInvestigationalAcoramidis is a small molecule stabilizer of transthyretin (TTR) for use in patients with TTR amyloidosis. … [L51958] Similar to the previously developed [tafamidis], acoramidis is used to stabilize TTR in its tetrameric form, preventing the formation of amyloidogenic monomers and the progression of amyloidosis
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: 3-(3-(3,5-dimethyl-1h-pyrazol-4-yl)propoxy)-4-fluorobenzoic acidOxycodegol
go.drugbank.com/drugs/DB14146InvestigationalThe lack of abuse potential is believed to be due to the drug's slow rate of entry into brain, a unique characteristic compared to others in the opioid class [A33997, A34016]. … Nektar Therapeutics has filed an application for FDA approval of Loxicodegol for use in the treatment of chronic lower back pain [L3263]
Categories: Heterocyclic Compounds with 4 or More Rings