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Pentaerythritol tetranitrate
go.drugbank.com/drugs/DB06154ApprovedWithdrawnIt is formed by reacting pentaerythritol (C5H12O4), an alcohol commonly used in paints and varnishes, with nitric acid (HNO2). The reacting solution is chilled to precipitate the PETN. … It is recognized by the FDA to be a coronary vasodilator in the treatment of heart conditions such as angina [L2395].
Products: Peritrate Tab 20mg, Peritrate Tab 10mgConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigational[T484] The currently approved product of conjugated estrogens was developed by Wyeth Ayerst and FDA approved in 2003.[L5608] … Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.
Mixtures: Esterified Estrogens and Methyltestosterone, Esterified Estrogens and MethyltestosteroneCategories: Genito Urinary System and Sex Hormones, conjugated estrogens and bazedoxifeneRupatadine
go.drugbank.com/drugs/DB11614ApprovedInvestigationalIt was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and liquid formulation for pediatric use. … Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria
Categories: Histamine H1 Antagonists, Non-SedatingProducts: RUPAFIN 10MG, URTIMED 10MGHydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedHydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing … Due to its potent and broad-spectrum antimicrobial actions, hydrogen peroxide is used in both liquid and gas form for preservative, disinfection and sterilization applications as an oxidative biocide [
Mixtures: Prevention Wound and Burn, QCare Oral Cleansing and Suctioning System, Q4Categories: Alimentary Tract and Metabolism, Antiseptics and DisinfectantsIvermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approved[L31453] Ivermectin is mainly used in humans in the treatment of onchocerciasis, but may also be effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and enterobiasis … With the advent of 2020 and the COVID-19 pandemic, ivermectin began garnering notoriety due to its off-label use for the prophylaxis and treatment of COVID-19.
Mixtures: Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbsCategories: Scabicides and Pediculicides, Antiparasitic Products, Insecticides and RepellentsPolyethylene glycol
go.drugbank.com/drugs/DB09287ApprovedInvestigationalVet approvedPolyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage. … [A190975] Molecular weights of PEGs vary by time of the polymerization process and the molecular weight represents the weighted average of the individual PEG molecules.
Mixtures: Gavilyte-N, Salinol Sol 160mgCategories: Alimentary Tract and MetabolismAstemizole
go.drugbank.com/drugs/DB00637ApprovedWithdrawnIt was withdrawn from market by the manufacturer in 1999 due to the potential to cause arrhythmias at high doses, especially when when taken with CYP inhibitors or grapefruit juice. … Astemizole is a long-acting, non-sedating second generation antihistamine used in the treatment of allergy symptoms.
Categories: Histamine H1 Antagonists, Non-SedatingProducts: Hismanal Suspension 2mg/ml, Hismanal Tab 10mgBetahistine
go.drugbank.com/drugs/DB06698ApprovedInvestigationalMénière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss. … It has a significant impact on both the physical and social functioning of affected individuals.
Synonyms: N-methyl-2-pyridineethanamine, N-methyl-2-(2-pyridinyl)ethanamineProducts: BETAVERT N 24MG, BETAVERT N 16MGAdenosine
go.drugbank.com/drugs/DB00640ApprovedInvestigational[A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … and [regadenson].
Mixtures: Lebody Bu W Renewal Up, Ginseng Royal Silk Eye 25mlCategories: Nucleic Acids, Nucleotides, and NucleosidesNalbuphine
go.drugbank.com/drugs/DB00844ApprovedInvestigationalIt appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors. … Nalbuphine is the only opioid analgesic that is not a controlled substance in the United States.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: N-cyclobutylmethyl-4,5α-epoxy-3,6α,14-morphinantriol