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Letrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigationalLetrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990. … [A190543,A1559,L11623,L11626] It is a third generation aromatase inhibitor like [exemestane] and [anastrozole], meaning it does not significantly affect cortisol, aldosterone, and thyroxine.
Products: SOLESTRASA-IN, LETROZOLO DOC GENERICIFludarabine
go.drugbank.com/drugs/DB01073ApprovedInvestigationalFludarabine is a chemotherapeutic agent used in the treatment of hematological malignancies. It is commonly marketed under the brand name Fludara.
Products: FLUDARABINA MYLAN GENERICS, FLUDARABINA IC PHARMAFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalHMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. … It is also the first entirely synthetic HMG-CoA reductase inhibitor and is structurally distinct from the fungal derivatives of this therapeutic class.
Products: FLUVASTATINA DOC GENERICI, FLUVASTATINA MYLAN GENERICSTiclopidine
go.drugbank.com/drugs/DB00208ApprovedIt is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. … Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke.
Products: TICLOPIDINA DOC GENERICI, TICLOPIDINA MYLAN GENERICSPyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalPyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos. … Other uses of pyrithione zinc include additive in antifouling outdoor paints and algaecide.
Synonyms: Pyridinethiol N-oxideMixtures: Neutrogena T/Gel Therapeutic, D-COL Personal Hygiene Convenience kitPheniramine
go.drugbank.com/drugs/DB01620Approved[A181628] It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. … Pheniramine is a first-generation antihistamine in the alkylamine class, similar to [brompheniramine] and [chlorpheniramine].
Mixtures: Rhume Et De LA Grippe (extra-fort), THERAFLU® N GRANULADO PARA SOLUCION ORALProducts: AVIL 45,5 MG/2 ML IM/IV AMPUL, 5 ML, LAMELAT 45.5 MG/ 2ML IM/IV ENJEKSIYONLUK ÇÖZELTI, 5 ADETDarifenacin
go.drugbank.com/drugs/DB00496ApprovedInvestigationalIt is unknown if M3 receptor selectivity is clinically advantageous in overactive bladder syndrome treatments. … This block reduces the urgency to urinate and so it should not be used in people with urinary retention.
Products: ENABLEX ® 15 MG TABLETAS DE LIBERACION PROLONGADA, ENABLEX ® 7.5 MG TABLETAS DE LIBERACION PROLONGADAChorionic Gonadotropin (Human)
go.drugbank.com/drugs/DB09126ApprovedInvestigationalVet approvedof human thyroid-stimulating hormone (TSH), while the beta sub units of these hormones differ in amino acid sequence. … In males, HCG also stimulates the production of gonadal steroid hormones by stimulating the interstitial cells (Leydig cells) of the testis to produce androgens.
Products: Pregnyl 5000 I. E. - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, MERIONAL® 75 UIRisedronic acid
go.drugbank.com/drugs/DB00884ApprovedInvestigationalRisedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111]. … It functions by preventing resorption of bone[FDA Label][A959].
Mixtures: RISEPLUS D3 35 MG/5600 IU EFERVESAN TABLET, 4 ADET, RISEPLUS D3 35 MG/2800 IU EFERVESAN TABLET, 12 ADETProducts: RISEDRONATO ARROW GENERICS, RISEDRONATO MYLAN GENERICSPancrelipase
go.drugbank.com/drugs/DB00085ApprovedInvestigationalPancrelipase, in general, is composed of a mixture of pancreatic enzymes which include amylases, lipases, and proteases. These enzymes are extracted from porcine pancreatic glands. … [L2509] The pancrelipase mixture was developed by Ortho-McNeil-Janssen Pharmaceuticals, Inc and FDA approved on April 12, 2010.
Products: CREON® CAPSULAS DE LIBERACION RETARADADA 10.000, KREON 20000PH EU LI EI HKM