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Albumin human
go.drugbank.com/drugs/DB00062ApprovedInvestigationalAlbumin represents approximately 50% of the total protein content in healthy humans [A40060]. … This is a biosimilar drug to existing human serum albumin and was approved for a biological license at both 5% and 25% concentrations by the FDA on June 21, 2018 [L3101].
Products: BUMINATE ALBUMINA AL 20 %, Octagam 100 mg/ml InfusionslösungPyridoxine
go.drugbank.com/drugs/DB00165ApprovedInvestigationalNutraceuticalVet approvedPyridoxine is used medically for the treatment of vitamin B6 deficiency and for the prophylaxis of isoniazid-induced peripheral neuropathy (due to [DB00951]'s mechanism of action which competitively inhibits … As its classification as a vitamin implies, Vitamin B6 (and pyridoxine) are essential nutrients required for normal functioning of many biological systems within the body.
Mixtures: Vitamine Du Groupe B Plus Fer - Liq, PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETProducts: Vitamin B6 100 mg, PIRIDOXINA 100 MGApomorphine
go.drugbank.com/drugs/DB00714ApprovedInvestigationalApomorphine is a non-ergoline dopamine D2 agonist indicated to treat hypomobility associated with Parkinson's. It was first synthesized in 1845 and first used in Parkinson's disease in 1884. … [A203618] Apomorphine has also been investigated as an emetic, a sedative, a treatment for alcoholism, and a treatment of other movement disorders.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol, (R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diolVenetoclax
go.drugbank.com/drugs/DB11581ApprovedInvestigationalVenetoclax is approximately 10 times more potent than navitoclax with regard to induction of apoptosis in CLL cells [A40022]. … Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label].
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: VENCLYXTO 10 MG FILM KAPLI TABLET, 10 ADET, VENCLYXTO 10 MG FILM KAPLI TABLET, 14 ADETMilrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigational[A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function and peripheral vasodilation in acute decongested heart failure. … Heart failure is a multifactorial condition that affects roughly 1-2% of the adult population.
Categories: Compounds used in a research, industrial, or household settingProducts: MILRINONA 10 MG/10 ML, MILRINONA 10 MG/ 10 MLAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalAzithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: AZYDROP®15 MG/G, ZITROMAX 200 MG/5ML ORAL SUSPANSIYON, 15 MLCyproterone acetate
go.drugbank.com/drugs/DB04839ApprovedInvestigationalIt is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females. … An anti-androgen that, in the form of its acetate (cyproterone acetate), also has progestational properties.
Mixtures: DONABELLA® 2 MG /0.035 MG, DONABELLA® 2 MG /0.035 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsTolnaftate
go.drugbank.com/drugs/DB00525ApprovedVet approvedTolnaftate is a synthetic over-the-counter anti-fungal agent. It may come as a cream, powder, spray, or liquid aerosol, and is used to treat jock itch, athlete's foot and ringworm.
Mixtures: Nail MDSynonyms: O-2-Naphthyl m,N-dimethylthiocarbanilate, m,N-Dimethylthiocarbanilic acid O-2-naphthyl esterRitonavir
go.drugbank.com/drugs/DB00503ApprovedInvestigationalIt is now more commonly used as a booster of other protease inhibitors and is available in both liquid formulations and as capsules. … Ritonavir is also available as a fixed-dose combination product with [DB09296] and [DB09297] as the FDA- and Health Canada-approved product Technivie.
Mixtures: ALUVIA (100 MG/25 MG), KALETRA 200 MG/50 MG FILM TABLET, 120 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InducersSapropterin
go.drugbank.com/drugs/DB00360ApprovedInvestigationalSapropterin (tetrahydrobiopterin or BH4) is a cofactor in the synthesis of nitric oxide.
Products: KUVAN® 100 MG, KUVAN 100 MG ÇÖZÜNEBİLİR TABLET, 120 ADET