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Displaying results 4601 - 4610 of 10000 in total
  1. Indication

    Systemic Mastocytosis With an Associated Hematological Neoplasm

    go.drugbank.com/conditions/DBCOND0135968
    Drugs: Avapritinib
    Synonyms: Systemic Mastocytosis With an Associated Hematologic Neoplasm, Systemic Mastocytosis With an Associated Hematological Neoplasm
  2. Drug

    Frespaciguat

    go.drugbank.com/drugs/DB21683
    Investigational

    Frespaciguat is under investigation in clinical trial NCT05612035 (Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With … The usage of the INN stem '-ciguat' in the name indicates that Frespaciguat is a guanylate cyclase activator and stimulator.

  3. Drug

    5-methyltetrahydrofolic acid

    go.drugbank.com/drugs/DB04789
    InvestigationalNutraceutical

    It is generated by methylenetetrahydrofolate reductase from 5,10-methylenetetrahydrofolate and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferases

    Categories: Enzymes and Coenzymes, Folic Acid and Derivatives
  4. Drug

    ChulaCov19 mRNA vaccine

    go.drugbank.com/drugs/DB16445
    Experimental

    The ChulaCov19 vaccine is mRNA-based and was developed in Thailand’s Chulalongkorn University in collaboration with the University of Pennsylvania in the US[L30673, L30678]. … Pre-clinical studies in mice and monkeys showed evidence that the vaccine facilitates an impressive generation of neutralizing antibodies[L30678].

  5. Drug

    Isopropyl myristate

    go.drugbank.com/drugs/DB13966
    Approved

    Isopropyl myristate has been largely studied and impulsed as a skin penetration enhancer. … Isopropyl myristate is a moisturizer with polar characteristics used in cosmetics and topical medical preparations to ameliorate the skin absorption.

    Categories: Scabicides and Pediculicides
  6. Indication

    Sickle Cell Disease

    go.drugbank.com/conditions/DBCOND0029334
    Drugs: Exagamglogene autotemcel · Lovotibeglogene autotemcel · Piracetam · Voxelotor
    Synonyms: Double heterozygous for Hb S and Hb D
  7. Drug

    Inecalcitol

    go.drugbank.com/drugs/DB04796
    Investigational

    Categories: Vitamin D and Analogues
  8. Drug

    Bentiromide

    go.drugbank.com/drugs/DB00522
    ApprovedWithdrawn

    Cases of headache and gastrointestinal disturbances have been reported with the use of bentiromide. Bentiromide is currently not available in the U.S. or Canada. … Bentiromide is a dipeptide that is used in the bentiromide test, which is a screening test for evaluating pancreatic exocrine function and monitoring the adequacy of supplemental pancreatic therapy.

    Categories: Indicators and Reagents
  9. Drug

    Collagen-polyvinylpyrrolidone

    go.drugbank.com/drugs/DB16525
    Investigational

    Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight PVP that has undergone γ irradiation[A227733]. … It is characterized by antifibrotic, fibrolytic, and immunomodulatory properties[A227733].

    Categories: Amino Acids, Peptides, and Proteins
  10. Drug

    Mimosine

    go.drugbank.com/drugs/DB01055
    Experimental

    Mimosine is an antineoplastic alanine-substituted pyridine derivative isolated from _Leucena glauca_.

    Categories: Amino Acids, Peptides, and Proteins