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SR-123781A
go.drugbank.com/drugs/DB05361InvestigationalSR-123781A is a synthetic hexadecasaccharide Factor IIa and Xa antagonist. It is under investigation by Sanofi-Aventis and Organon for the treatment of thrombosis and acute coronary syndromes (ACS).
Categories: Heparin and similarsMK-4721
go.drugbank.com/drugs/DB05933InvestigationalMK-4721 is a fully human monoclonal antibody directed to Agensys’ proprietary target Prostate Stem Cell Antigen (PSCA), an antigen expressed at significant levels on tumor cells from the majority of patients … with all stages of prostate, pancreatic and bladder cancers.
Categories: Amino Acids, Peptides, and ProteinsGirentuximab
go.drugbank.com/drugs/DB05304InvestigationalGirentuximab is a monoclonal chimeric (mouse/human) antibody directed against carbonic anhydrase IX, an antigen expressed in 95% of clear cell renal cell carcinomas (RCC).
Categories: Amino Acids, Peptides, and ProteinsPyrimethamine
go.drugbank.com/drugs/DB00205ApprovedInvestigationalVet approvedOne of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Categories: artesunate, sulfalene and pyrimethamine, artesunate, sulfadoxine and pyrimethaminePolistes fuscatus venom protein
go.drugbank.com/drugs/DB10959ApprovedPolistes fuscatus venom protein is an extract of Polistes fuscatus venom. Polistes fuscatus venom protein is used in allergenic testing.
Categories: Bee and Wasp VenomNomegestrol acetate
go.drugbank.com/drugs/DB13981ApprovedNomegestrol acetate, also known as NOMAC, is a progestin used in oral contraceptives, menopausal hormone therapy, and for the treatment of gynecological disorders.
Mixtures: FEMIDEN® 1.5 MG/2.5MG TABLETAS RECUBIERTASCategories: Combination Contraceptives (with Estrogen and derivatives)Artesunate
go.drugbank.com/drugs/DB09274ApprovedInvestigational[A203948] Artesunate was granted FDA approval on 26 May 2020.[L14099] … Artesunate is indicated for the initial treatment of severe malaria.[L14099] The World Health Organization recommends artesunate as first line treatment for severe malaria.
Categories: Artemisinin and derivatives, artesunate and mefloquineMoricizine
go.drugbank.com/drugs/DB00680ApprovedWithdrawnAn antiarrhythmia agent used primarily for ventricular rhythm disturbances.
Categories: Antiarrhythmics, Class I, Antiarrhythmics, Class IcSynonyms: ethyl 10-(β-N-morpholinylpropionyl)phenothiazine-2-carbamateLapyrium
go.drugbank.com/drugs/DB09376ApprovedLapyrium is a quaternary ammonium cation used as a surfactant, antistatic agent, and biocide in various cosmetic products [A19426]. It is commonly found formulated as lapyrium chloride.
Malacidin B
go.drugbank.com/drugs/DB14052ExperimentalMalacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. … Malacidins are 10-member macrocycle lipopeptides discovered via gene sequencing and bioinformatic analysis.
Categories: Amino Acids, Peptides, and Proteins