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Displaying results 4621 - 4630 of 10000 in total
  1. Target

    Transient receptor potential cation channel subfamily V member 5

    go.drugbank.com/bio_entities/BE0005112
    TransporterHumans

    Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590). Required for normal Ca(2+) reabsorption in the kidney distal convoluted tubu...

    Polypeptides: Transient receptor potential cation channel subfamily V member 5
  2. Target

    Solute carrier family 2, facilitated glucose transporter member 5

    go.drugbank.com/bio_entities/BE0005216
    TransporterHumans

    Functions as a fructose transporter that has only low activity with other monosaccharides (PubMed:16186102, PubMed:17710649, PubMed:28083649, PubMed:29548810, PubMed:8333543). Can mediate the uptake of 2-deoxyglucose, but with low effici...

    Polypeptides: Solute carrier family 2, facilitated glucose transporter member 5Synonyms: GLUT-5, Glucose transporter type 5, small intestine
  3. Drug

    Manganese cation

    go.drugbank.com/drugs/DB06757
    ApprovedInvestigationalNutraceutical

    [A263687, A263662] In humans, manganese regulates several physiological processes by acting as a cofactor for proteins [A263657, A263662, A263667] making it an essential metal for normal development and … Manganese is a transition metal that was first described in the 19th and 20th centuries.

    Synonyms: MANGANESE(2+), MANGANESE ION(2+)Mixtures: TRACUTIL® 10 ML AMPOLLAS, Calcium With Mg Zn Mn Cu CR Si and Vit. C & D
  4. Drug

    Glycine

    go.drugbank.com/drugs/DB00145
    ApprovedInvestigationalNutraceuticalVet approved

    A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.

    Mixtures: AMINOPLASMAL® 10% E, AMINOPLASMAL® 10% EProducts: GLICINA IRRIGACION 1.5% M/V, GLICINA IRRIGACION USP (1.5% W/V)BOLSA POR 3000 ML
  5. Drug

    Phenylbutazone

    go.drugbank.com/drugs/DB00812
    ApprovedVet approvedWithdrawn

    It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). … A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis.

    Categories: Heterocyclic Compounds, 1-Ring, Non COX-2 selective NSAIDSSynonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione
  6. Drug

    Tenecteplase

    go.drugbank.com/drugs/DB00031
    ApprovedInvestigational

    It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids … Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA).

    Products: METALYSE 10000 U (50 MG) ENJEKSIYONLUK TOZ ICEREN FLAKON, 1 ADET, TENECTEPLASE BOEHRINGER INGELHEIM PHARMA KG
  7. Drug

    Buclizine

    go.drugbank.com/drugs/DB00354
    Approved

    It was manufactured by Stuart Pharms and initially approved by the FDA in 1957. … [L6217] Following this, it was touted to be effective as an appetite stimulant in children when administered in the syrup form, however, this indication has not been validated.

    Synonyms: 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazineInternational brands: Bucladin-S
  8. Drug

    Interferon alfa-2a

    go.drugbank.com/drugs/DB00034
    ApprovedInvestigationalWithdrawn

    Interferon a (human leukocyte protein moiety reduced). A type I interferon consisting of 165 amino acid residues with lysine in position 23. … It is used extensively as an antiviral or antineoplastic agent. An oral form is being developed by Amarillo Biosciences.

    Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsInternational brands: Roferon A
  9. Drug

    Nalidixic acid

    go.drugbank.com/drugs/DB00779
    ApprovedWithdrawn

    Nalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.

    Synonyms: 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure, 3-carboxy-1-ethyl-7-methyl-1,8-naphthyridin-4-oneCategories: 4-Quinolones, Heterocyclic Compounds, 2-Ring
  10. Drug

    Pinazepam

    go.drugbank.com/drugs/DB13335
    Investigational

    Categories: Heterocyclic Compounds, 2-RingProducts: DOMAR CAPSULE 5 mg