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Deudextromethorphan
go.drugbank.com/drugs/DB19054InvestigationalDeudextromethorphan is under investigation in clinical trial NCT02153502 (Efficacy, Safety, and Tolerability Study of AVP-786 as an Adjunctive Therapy in Patients With Major Depressive Disorder With an
Zuranolone
go.drugbank.com/drugs/DB15490ApprovedInvestigationalbinding to a non-benzodiazepine site on the receptor. … Zuranolone is a neuroactive steroid that acts as a positive allosteric modulator of the GABA<sub>A</sub> receptors.
Categories: Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive ModulatorEVT 302
go.drugbank.com/drugs/DB06057InvestigationalEVT 302 is an orally active, potent, highly selective and reversible inhibitor of MAO-B. It is in the development for smoking cessation, and potential for disease modification in Alzheimer's disease.
P-113D
go.drugbank.com/drugs/DB04987ExperimentalIt is being pursued as a potential treatment for cystic fibrosis by Demegen, Inc. … P-113D is a novel 12 amino-acid antimicrobial peptide drug derived from histatins, which are compounds found naturally in human saliva.
IMC-1C11
go.drugbank.com/drugs/DB06101ExperimentalIMC-1C11 is an anti-angiogenesis agent. … It is a chimeric anti-kinase insert domain-containing receptor (KDR) antibody that blocks VEGFR-KDR interaction and inhibits VEGFR-induced endothelial cell proliferation.
Estramustine phosphate
go.drugbank.com/drugs/DB14674ApprovedA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Hexoprenaline
go.drugbank.com/drugs/DB08957ApprovedWithdrawnHexoprenaline is a stimulant of beta 2 adrenergic receptors. It is used as a bronchodilator, antiasthmatic, and tocolytic agent.
Categories: Adrenergic beta-2 Receptor AgonistsPhosphonoacetic Acid
go.drugbank.com/drugs/DB02823ExperimentalA simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent. [PubChem]
Candoxatril
go.drugbank.com/drugs/DB00616ExperimentalCandoxatril is the orally-active prodrug of candoxatrilat (UK-73967), a potent neutral endopeptidase (NEP) inhibitor.