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Displaying results 4681 - 4690 of 10000 in total
  1. Drug

    Bryostatin 1

    go.drugbank.com/drugs/DB11752
    Investigational

    Bryostatin 1 has been investigated for the treatment of HIV Infection and Alzheimer's Disease.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: Bryostatin 1, Bryostatin-1
  2. Drug

    Tetrahydrocannabivarin

    go.drugbank.com/drugs/DB11755
    Investigational

    Compared to THC which demonstrates its effects through weak partial agonist activity of both endocannabinoid receptors Cannabinoid-1 (CB1R) and Cannabinoid-2 (CB2R), THCV acts as a CB1 antagonist and a … These effects are largely mediated through two members of the G-protein coupled receptor family, cannabinoid receptors 1 and 2 (CB1 and CB2)[A32585].

    Categories: Serotonin 5-HT1 Receptor Agonists
  3. Drug

    Istradefylline

    go.drugbank.com/drugs/DB11757
    ApprovedInvestigational

    [A184067] Unlike standard dopaminergic therapies for Parkinson's, Istradefylline targets adenosine A<sub>2A</sub> receptors in the basal ganglia.

    Categories: MATE 1 Inhibitors, MATE 2 Inhibitors
  4. Drug

    Cenicriviroc

    go.drugbank.com/drugs/DB11758
    Investigational

    Cenicriviroc has been used in trials studying the treatment of HIV-infection/AIDS, AIDS Dementia Complex, Nonalcoholic Steatohepatitis, Human Immunodeficiency Virus, and HIV-1-Associated Cognitive Motor

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Pevonedistat

    go.drugbank.com/drugs/DB11759
    Investigational

    Pevonedistat has been used in trials studying the treatment of Lymphoma, Solid Tumors, Multiple Myeloma, Hodgkin Lymphoma, and Metastatic Melanoma, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    PF-04991532

    go.drugbank.com/drugs/DB11765
    Investigational

    PF-04991532 has been used in trials studying the basic science of Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus, Type 2, and Glucose Metabolism Disorders.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    AZD-1305

    go.drugbank.com/drugs/DB11766
    Investigational

    AZD1305 has been used in trials studying the treatment and basic science of Atrial Flutter, Atrial Fibrillation, and Left Ventricle Function.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  8. Drug

    Sarilumab

    go.drugbank.com/drugs/DB11767
    ApprovedInvestigational

    cascades of IL-6. … Sarilumab is a fully human anti-interleukin 6 (IL-6) receptor monoclonal IgG1 antibody that binds to both membrane-bound and soluble IL-6 receptor forms, thus blocking the cis- and trans-inflammatory signalling

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
  9. Drug

    Imidapril

    go.drugbank.com/drugs/DB11783
    Investigational

    Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.

    Categories: Heterocyclic Compounds, 1-RingProducts: TANATRIL TABLETS 5 mg, ทานาทริล 5 มก. ชนิดเม็ด
  10. Drug

    Capmatinib

    go.drugbank.com/drugs/DB11791
    ApprovedInvestigational

    [A199122] This co-occurrence has made c-Met a desirable target in the treatment of NSCLC. … Capmatinib is a small molecule kinase inhibitor targeted against c-Met (a.k.a. hepatocyte growth factor receptor [HGFR]), a receptor tyrosine kinase that, in healthy humans, activates signaling cascades

    Categories: MATE 2-K Inhibitors, MATE 1 Inhibitors