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Sulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigationalIt is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA). … [L39065, A255582] Metabolized by intestinal bacteria, sulfasalazine is broken down into [mesalazine] and [sulfapyridine], 2 compounds that carry out the main pharmacological activity of sulfasalazine.
Categories: Non COX-2 selective NSAIDSSynonyms: 柳氮磺吡啶, 2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acidPanthenol
go.drugbank.com/drugs/DB11204ApprovedPanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions
Mixtures: bdr Re-lax 3 multiple level serum highly-potential youth, Anbiser B-HA Hyaluronic Acid NourishingCategories: Vitamin B ComplexSibutramine
go.drugbank.com/drugs/DB01105ApprovedIllicitWithdrawnIt is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … In October 2010, Sibutramine was withdrawn from Canadian and U.S. markets due to concerns that the drug increases the risk of heart attack and stroke in patients with a history of heart disease.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: SEMIT® CAPSULAS POR 15MG., TALLARME®HIV viral load undetectable
go.drugbank.com/conditions/DBCOND0148838Synonyms: Virologically suppressed (HIV-1 RNA less than 50 copies per mL)Pegmusirudin
go.drugbank.com/drugs/DB19220InvestigationalPegmusirudin is under investigation in clinical trial NCT00074620 (A Clinical Study to Assess the Safety of Peg-hirudin (SPP200) Compared to Heparin in Patients Who Are on Haemodialysis).
Synonyms: PEG-HirudinIpratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigational[A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. … Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent.
Mixtures: SALBUTAMOLO E IPRATROPIO BROMURO EG, BERODUAL® HFASynonyms: bromuro de ipratropioCalcium polycarbophil
go.drugbank.com/drugs/DB14684ApprovedBased on its chemical structure, it is a synthetic polymer of polyacrylic acid cross-linked with divinyl glycol presenting a calcium atom as a counter-ion. … Calcium polycarbophil is a stool stabilizer.
Categories: Compounds used in a research, industrial, or household settingProducts: Fiber Lax, FIBROSYL®Potassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. … The FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release
Mixtures: Peg-3350, PEG-3350 and ElectrolytesInternational brands: Slow-K, Micro-KEfavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationalEfavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human … Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with a
Mixtures: Symfi Lo, Symfi LoCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalCalcitriol plays a role in plasma calcium regulation in concert with parathyroid hormone (PTH) by enhancing absorption of dietary calcium and phosphate from the gastrointestinal tract, promoting renal … calcitriol has been demonstrated to increase energy efficiency by suppressing UCP2 expression, which is modulated by signaling pathways of classical nuclear receptors (nVDR), where calcitriol acts as a
Categories: Vitamin D and Analogues, Cytochrome P-450 SubstratesSynonyms: 1-alpha-25-Dihydroxyvitamin D3, (1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol