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Displaying results 461 - 470 of 10000 in total
  1. Drug

    Epinephrine

    go.drugbank.com/drugs/DB00668
    ApprovedInvestigationalVet approved

    On August 16, 2018, Teva Pharmaceuticals USA gained approval to market its generic epinephrine auto-injector in 0.3 mg and 0.15 mg strengths [L4353]. … Though it has long been used in the treatment of hypersensitivity reactions, epinephrine in the auto-injector form (EpiPen) has been available since 1987 in the USA.

    Synonyms: 4-((1R)-1-HYDROXY-2-(METHYLAMINO)ETHYL)-1,2-BENZENEDIOL, 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediolInternational brands: Epi EZ Pen JR
  2. Drug

    Ketorolac

    go.drugbank.com/drugs/DB00465
    ApprovedInvestigational

    Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.

    Mixtures: Ixoba M, Acunivive 90Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-Ring
  3. Drug

    Gentamicin

    go.drugbank.com/drugs/DB00798
    ApprovedInvestigationalVet approved

    Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963. … [A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity

    Mixtures: BELOGENT %0,05+%0,1 KREM, 30 G, BELOGENT %0,05+%0,1 MERHEM, 30 GInternational brands: G-Mycin
  4. Drug

    Didanosine

    go.drugbank.com/drugs/DB00900
    ApprovedInvestigational

    A dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by a hydrogen.

    Synonyms: 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 2',3'-dideoxyinosineCategories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Sildenafil

    go.drugbank.com/drugs/DB00203
    ApprovedInvestigational

    The result of doing so allows cGMP present in both the penis and pulmonary vasculature to elicit smooth muscle relaxation and vasodilation that subsequently facilitates relief in pulmonary arterial hypertension … the public in 1998 [A175732], continues to see millions of prescriptions written for it internationally.

    Mixtures: DAPOXIL 30/50 MG FILM KAPLI TABLET,18 FILM KAPLI TABLET, DAPOKSEL 30 MG/50 MG FILM TABLET ,3 FILM TABLETCategories: Drugs Used in Erectile Dysfunction
  6. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids. … A compound formed in the liver from ammonia produced by the deamination of amino acids.

    Mixtures: ÜRESAL FORTE %10 + %10 MERHEM (50 G), UREACORT YAĞLI %0,5 + %10 KREM (30 G)Products: UBIT TABLET 100 MG, NUTRAPLUS KREM %10, 60 G
  7. Drug

    Potassium Iodide

    go.drugbank.com/drugs/DB06715
    ApprovedInvestigational

    SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy. … Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperthyroidism (also known as thyroid storm or thyrotoxic crisis

    Mixtures: TRACUTIL® 10 ML AMPOLLAS, ADDAMEL N 20 AMPULProducts: JODID 200 MCG TABLET, 100 ADET, JODID 200 MCG TABLET, 50 ADET
  8. Drug

    Pentoxifylline

    go.drugbank.com/drugs/DB00806
    ApprovedInvestigational

    [A226608] Pentoxifylline has been marketed in Europe since 1972; PTX extended-release tablets sold under the trade name TRENTAL by US Pharm Holdings were first approved by the FDA on Aug 30, 1984, but … [A226410, A226415, A226455] More recently, PTX has been suggested as a possible treatment for COVID-19-induced pulmonary complications due to its ability to regulate the production of inflammatory cytokines

    Mixtures: Betamethasone Dipropionate 0.05% / Minoxidil 5% / Niacinamide 2% / Pentoxifylline 0.5%Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household setting
  9. Drug

    Tranexamic acid

    go.drugbank.com/drugs/DB00302
    ApprovedInvestigational

    It possesses a similar mechanism of action to [aminocaproic acid] but is approximately 10-fold more potent. … [L31883] It was first patented in 1957[A230108] and received its initial US approval in 1986.[L31858]

    Synonyms: trans-4-aminomethylcyclohexane-1-carboxylic acidProducts: TRANSAMINE 100 MG/ML IV ENJ COZELTI, 10 ADET, TRANSAMINE 50 MG/ML IV ENJ COZELTI, 5 ML
  10. Drug

    Lovastatin

    go.drugbank.com/drugs/DB00227
    ApprovedInvestigational

    [A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … were found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40%.

    Synonyms: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate, 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactoneProducts: MEVACOR 10 MG, LOVASTATINA EG