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Danazol
go.drugbank.com/drugs/DB01406ApprovedInvestigationalDanazol has been used in the treatment of endometriosis and some benign breast disorders. … A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: DANASIN 50 MG KAPSUL, 100 ADET, DANASIN 100 MG KAPSUL, 100 ADETEfavirenz
go.drugbank.com/drugs/DB00625ApprovedInvestigationalFor HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen. … Efavirenz (brand names Sustiva® and Stocrin®) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and is used as part of highly active antiretroviral therapy (HAART) for the treatment of a human
Mixtures: Efatriten 600 mg/200 mg/245 mg Filmtabletten, Padviram 600 mg/200 mg/245 mg - FilmtablettenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalLong-acting formulations of psychostimulants (such as [DB00422], [DB01576], and [DB01255]) are typically considered the most effective and first-line treatment for ADHD in adults and children as recommended … is a limiting factor associated with the use of stimulant medications such as [DB00422], [DB01576], and [DB01255].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: STRATTERA 10 MG, audalis 10 mg FilmtablettenCalfactant
go.drugbank.com/drugs/DB06415ApprovedInvestigationalEach milliliter of calfactant contains 35mg of phospholipids (including 26 mg phosphatidylcholine of which 16 mg is disaturated phosphatidylcholine) and 0.65mg of proteins including surfactant-associated … Calfactant has been shown to decrease the incidence of respiratory distress syndrome, mortality due to respiratory distress syndrome, and air leaks associated with respiratory distress syndrome in clinical
Products: ALVEOFACT 50 MG/1.2 ML INTRATRAKEAL STERİL APİROJEN SÜSPANSİYON, 1 ADET, INFASURF 35 MG/ML INTRATRAKEAL SÜSPANSIYON ,6 MLEstramustine
go.drugbank.com/drugs/DB01196ApprovedWithdrawnA nitrogen mustard linked to estradiol, usually as phosphate; used to treat prostatic neoplasms; also has radiation protective properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: 17β-Estradiol 3-(bis(2-chloroethyl)carbamate), Estradiol 3-(N,N-bis(2-chloroethyl)carbamate)Cysteamine
go.drugbank.com/drugs/DB00847ApprovedInvestigational[L15611] On August 25th 2020, the first ophthalmic solution for cystinosis requiring only 4 daily treatments was granted FDA approval.
Products: CYSTAGON ® 150 MG, CYSTAGON ® 50 MG CAPSULASKetoconazole
go.drugbank.com/drugs/DB01026ApprovedInvestigational[A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in 1981. … However, it was discovered that ketoconazole produces frequent gastrointestinal side effects and dose-related hepatitis.
International brands: Orifungal MMixtures: CLINDAMICINA/KETOCONAZOL 100 MG/400MGTetracaine
go.drugbank.com/drugs/DB09085ApprovedInvestigationalVet approvedTetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
Mixtures: OTIMISIN DAMLA, 10 ML, Pliaglis 70 mg/g + 70 mg/g CremeProducts: Pontocaine 5 mg/ml, Tetracaine (Base)Lorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalLorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. … [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977.
Products: ATIVAN EXPIDET 1 MG TABLET, 50 ADET, ATIVAN EXPIDET 2.5 MG TABLET, 50 ADETAminophylline
go.drugbank.com/drugs/DB01223ApprovedInvestigationalSimilar to other theophyllines, aminophylline is indicated for the treatment of lung diseases such as asthma, chronic bronchitis, and COPD. … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: AMINOCARDOL 10 ML 240 MG 100 AMPUL, TECAR 240 MG/10 ML IV INFUZYON COZELTISI ICEREN AMPUL, 100 ADET